Lapatinib

major histocompatibility complex, class II, DR beta 1 ; Homo sapiens







9 Article(s)
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1 31383939 HLA-DRB1*07:01 and lapatinib-induced hepatotoxicity: a systematic review and meta-analysis. 2020 Feb 7
2 28786423 Characterisation of the HLA-DRB1*07:01 biomarker for lapatinib-induced liver toxicity during treatment of early-stage breast cancer patients with lapatinib in combination with trastuzumab and/or taxanes. 2018 May 22 11
3 28253087 Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back-Looking Forward to Next-Generation Innovation. 2017 Mar 3
4 25987243 Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1*07:01. 2016 Apr 2
5 27989141 No Evidence for Drug-Specific Activation of Circulating T Cells from Patients with HLA-DRB1*07:01-Restricted Lapatinib-Induced Liver Injury. 2016 Dec 19 2
6 26098642 The Possible Mechanism of Idiosyncratic Lapatinib-Induced Liver Injury in Patients Carrying Human Leukocyte Antigen-DRB1*07:01. 2015 5
7 26265235 Rash in lapatinib-treated patients is not associated with human leukocyte antigen polymorphisms. 2015 2
8 24687830 Prospective validation of HLA-DRB1*07:01 allele carriage as a predictive risk factor for lapatinib-induced liver injury. 2014 Aug 1 5
9 22357454 Lapatinib-induced liver injury characterized by class II HLA and Gilbert's syndrome genotypes. 2012 Apr 1