Protein Name MCL1 apoptosis regulator, BCL2 family member
Organism Homo sapiens
Gene ID 4170
Gene Symbol


UniProt Q07820 (MCL1_HUMAN), A0A087WT64 (A0A087WT64_HUMAN), C8YZ26 (C8YZ26_HUMAN)
Relationships Total Number of functionally related compound(s) : 1015
Total Number of Articles : 1995

MCL1 apoptosis regulator, BCL2 family member

Gene Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]

  • induced myeloid leukemia cell differentiation protein Mcl-1
  • BCL2 family apoptosis regulator
  • MCL1, BCL2 family apoptosis regulator
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