Lapatinib

SRC proto-oncogene, non-receptor tyrosine kinase ; Homo sapiens







12 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34382727 miR-221 confers lapatinib resistance by negatively regulating p27kip1 in HER2-positive breast cancer. 2021 Oct 4
2 28158234 Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer. 2017 1
3 26621843 The erbB3- and IGF-1 receptor-initiated signaling pathways exhibit distinct effects on lapatinib sensitivity against trastuzumab-resistant breast cancer cells. 2016 Jan 19 1
4 26643609 Niclosamide inhibits epithelial-mesenchymal transition and tumor growth in lapatinib-resistant human epidermal growth factor receptor 2-positive breast cancer. 2016 Feb 1
5 27756261 Inhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways. 2016 Oct 19 1
6 25865888 Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains. 2015 Apr 21 1
7 24200972 Src and CXCR4 are involved in the invasiveness of breast cancer cells with acquired resistance to lapatinib. 2014 5
8 24887236 Epidermal growth factor-receptor activation modulates Src-dependent resistance to lapatinib in breast cancer models. 2014 May 5 10
9 25350844 Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models. 2014 3
10 23913825 SRC family kinases as novel therapeutic targets to treat breast cancer brain metastases. 2013 Sep 15 1
11 22389470 HER2 as therapeutic target for overcoming ATP-binding cassette transporter-mediated chemoresistance in small cell lung cancer. 2012 Apr 1
12 21499296 Phosphoproteomic mass spectrometry profiling links Src family kinases to escape from HER2 tyrosine kinase inhibition. 2011 Oct 6 2