Protein Name SRC proto-oncogene, non-receptor tyrosine kinase
Organism Homo sapiens
Gene ID 6714
Gene Symbol


UniProt P12931 (SRC_HUMAN)
Relationships Total Number of functionally related compound(s) : 2142
Total Number of Articles : 4632

SRC proto-oncogene, non-receptor tyrosine kinase

Gene Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

  • proto-oncogene tyrosine-protein kinase Src
  • proto-oncogene c-Src
  • protooncogene SRC, Rous sarcoma
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