Lapatinib

zinc fingers and homeoboxes 2 ; Homo sapiens







6 Article(s)
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Title
Pub. Year
#Total Relationships
1 28744398 Kinase inhibitors of HER2/AKT pathway induce ERK phosphorylation via a FOXO-dependent feedback loop. 2017 4
2 26623720 Immunohistochemical prediction of lapatinib efficacy in advanced HER2-positive breast cancer patients. 2016 Jan 5 1
3 23365119 Relief of feedback inhibition of HER3 transcription by RAF and MEK inhibitors attenuates their antitumor effects in BRAF-mutant thyroid carcinomas. 2013 May 1
4 21464044 The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models. 2011 May 15 1
5 19853943 Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK. 2009 Dec 2
6 16452222 Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells. 2006 Feb 1 1