| 1 |
34159337 | Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen. | 2021 Jun 15 |
1 |
| 2 |
34399705 | A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancer. | 2021 Aug 16 |
1 |
| 3 |
28423638 | HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E. | 2017 Mar 21 |
1 |
| 4 |
28744398 | Kinase inhibitors of HER2/AKT pathway induce ERK phosphorylation via a FOXO-dependent feedback loop. | 2017 |
3 |
| 5 |
29156708 | A preclinical evaluation of the MEK inhibitor refametinib in HER2-positive breast cancer cell lines including those with acquired resistance to trastuzumab or lapatinib. | 2017 Oct 17 |
3 |
| 6 |
25449780 | Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib. | 2015 Jan 28 |
1 |
| 7 |
25596742 | Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2. | 2015 Feb 10 |
2 |
| 8 |
26081723 | EGFR and HER2 signals play a salvage role in MEK1-mutated gastric cancer after MEK inhibition. | 2015 Aug |
1 |
| 9 |
23441129 | Inhibition of the growth of patient-derived pancreatic cancer xenografts with the MEK inhibitor trametinib is augmented by combined treatment with the epidermal growth factor receptor/HER2 inhibitor lapatinib. | 2013 Feb |
1 |
| 10 |
23531216 | MEK inhibition increases lapatinib sensitivity via modulation of FOXM1. | 2013 |
4 |
| 11 |
21464044 | The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models. | 2011 May 15 |
1 |
| 12 |
21499301 | Roles of BIM induction and survivin downregulation in lapatinib-induced apoptosis in breast cancer cells with HER2 amplification. | 2011 Sep 29 |
1 |
| 13 |
20088787 | Ras-induced resistance to lapatinib is overcome by MEK inhibition. | 2010 Mar |
4 |
| 14 |
19853943 | Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK. | 2009 Dec |
4 |