11 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 34239043 | A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers. | 2021 Aug | 1 |
2 | 30021909 | Tyrosine Kinase Inhibitors Increase MCL1 Degradation and in Combination with BCLXL/BCL2 Inhibitors Drive Prostate Cancer Apoptosis. | 2018 Nov 1 | 1 |
3 | 30305055 | Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL. | 2018 Oct 11 | 1 |
4 | 28415602 | ERRF sensitizes ERBB2-positive breast cancer cells to lapatinib treatment likely by attenuating MCL1 and ERBB2 expression. | 2017 May 30 | 2 |
5 | 25789974 | Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer. | 2015 Mar 19 | 2 |
6 | 22219388 | Obatoclax and lapatinib interact to induce toxic autophagy through NOXA. | 2012 Apr | 1 |
7 | 22357666 | Lapatinib and obatoclax kill tumor cells through blockade of ERBB1/3/4 and through inhibition of BCL-XL and MCL-1. | 2012 May | 1 |
8 | 20571878 | Anti-invasion, anti-proliferation and anoikis-sensitization activities of lapatinib in nasopharyngeal carcinoma cells. | 2011 Dec | 1 |
9 | 20855960 | Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo. | 2010 Nov 1 | 5 |
10 | 19823038 | Inhibition of MCL-1 enhances lapatinib toxicity and overcomes lapatinib resistance via BAK-dependent autophagy. | 2009 Nov | 4 |
11 | 18544666 | Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation. | 2008 Sep | 2 |