Protein Name nuclear receptor subfamily 4 group A member 1
Organism Homo sapiens
Gene ID 3164
Gene Symbol

NR4A1

UniProt P22736 (NR4A1_HUMAN), A0A024R126 (A0A024R126_HUMAN), Q6ZMM6 (Q6ZMM6_HUMAN), F5GXF0 (F5GXF0_HUMAN)
Relationships Total Number of functionally related compound(s) : 657
Total Number of Articles : 1026
Description

nuclear receptor subfamily 4 group A member 1

Gene Summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

synonyms
  • nuclear receptor subfamily 4immunitygroup A member 1
  • ST-59
  • TR3 orphan receptor
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Properties