Lapatinib

KRAS proto-oncogene, GTPase ; Homo sapiens







7 Article(s)
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1 32274564 Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer. 2020 May 1
2 27108243 Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial. 2016 Jun 1
3 27165728 Colorectal Cancer Yields to Dual HER2 Blockade. 2016 Jul 1
4 22458846 Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation. 2013 Aug 1
5 23076814 EGFR and HER2 inhibition in pancreatic cancer. 2013 Jun 1
6 21271222 KRAS-mutated non-small cell lung cancer cells are responsive to either co-treatment with erlotinib or gefitinib and histone deacetylase inhibitors or single treatment with lapatinib. 2011 Apr 2
7 20103665 Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status. 2010 Feb 1 2