Tamoxifen


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3004 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 1512
2 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 371
3 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 237
4 progesterone receptor PRGR_HUMAN PGR Homo sapiens 5241 863 181
5 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 120
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 118
7 nuclear receptor subfamily 4 group A member 1 NR4A1_HUMAN NR4A1 Homo sapiens 3164 657 115
8 estrogen receptor 2 ESR2_HUMAN ESR2 Homo sapiens 2100 856 107
9 estrogen receptor 1 (alpha) ESR1_MOUSE Esr1 Mus musculus 13982 611 103
10 estrogen receptor 1 ESR1_RAT Esr1 Rattus norvegicus 24890 683 96
11 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 95
12 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 72
13 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 70
14 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 68
15 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 66
16 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 66
17 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 61
18 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 59
19 G protein-coupled estrogen receptor 1 GPER1_HUMAN GPER1 Homo sapiens 2852 290 56
20 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 52
21 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 50
22 epiregulin EREG_HUMAN EREG Homo sapiens 2069 498 49
23 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 48
24 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 44
25 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 44
26 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 43
27 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 41
28 calmodulin 1 CALM1_HUMAN CALM1 Homo sapiens 801 1320 34
29 sex hormone binding globulin SHBG_HUMAN SHBG Homo sapiens 6462 621 33
30 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 33
31 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 31
32 progesterone receptor PRGR_RAT Pgr Rattus norvegicus 25154 237 29
33 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 29
34 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 28
35 prolactin PRL_RAT Prl Rattus norvegicus 24683 1247 28
36 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 27
37 gonadotropin releasing hormone 1 GON1_HUMAN GNRH1 Homo sapiens 2796 1184 25
38 proline rich transmembrane protein 2 PRRT2_HUMAN PRRT2 Homo sapiens 112476 1000 25
39 cytochrome P450 family 19 subfamily A member 1 CP19A_HUMAN CYP19A1 Homo sapiens 1588 827 25
40 nuclear receptor corepressor 2 NCOR2_HUMAN NCOR2 Homo sapiens 9612 95 24
41 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 24
42 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 24
43 gene trap ROSA 26, Philippe Soriano - Gt(ROSA)26Sor Mus musculus 14910 34 23
44 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 22
45 prolactin PRL_HUMAN PRL Homo sapiens 5617 1285 22
46 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 21
47 nuclear receptor corepressor 1 NCOR1_HUMAN NCOR1 Homo sapiens 9611 98 20
48 protein kinase C alpha KPCA_HUMAN PRKCA Homo sapiens 5578 1062 20
49 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 19
50 sulfotransferase family 1A member 1 ST1A1_HUMAN SULT1A1 Homo sapiens 6817 592 19