| 1 |
34020697 | Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant. | 2021 May 21 |
1 |
| 2 |
34326682 | Cx43 deficiency confers EMT-mediated tamoxifen resistance to breast cancer via c-Src/PI3K/Akt pathway. | 2021 |
2 |
| 3 |
34407787 | Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells. | 2021 Aug 18 |
2 |
| 4 |
32084531 | Regulation of KLF4 by posttranslational modification circuitry in endocrine resistance. | 2020 Jun |
2 |
| 5 |
32547094 | SRC Promotes Tamoxifen Resistance in Breast Cancer via Up-Regulating SIRT1. | 2020 |
16 |
| 6 |
30206184 | SOX9/FXYD3/Src Axis Is Critical for ER+ Breast Cancer Stem Cell Function. | 2019 Jan |
1 |
| 7 |
30304547 | Tamoxifen ameliorates obstructive nephropathy through Src and the PI3K/Akt/mTOR pathway. | 2019 Jan |
5 |
| 8 |
31195751 | Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer. | 2019 Jun 5 |
4 |
| 9 |
29720121 | C-Cbl reverses HER2-mediated tamoxifen resistance in human breast cancer cells. | 2018 May 2 |
4 |
| 10 |
30076704 | AhR ligand aminoflavone suppresses α6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells. | 2018 Jan |
2 |
| 11 |
28751463 | Dual Src Kinase/Pretubulin Inhibitor KX-01, Sensitizes ERα-negative Breast Cancers to Tamoxifen through ERα Reexpression. | 2017 Nov |
1 |
| 12 |
27308830 | Src Is a Potential Therapeutic Target in Endocrine-Resistant Breast Cancer Exhibiting Low Estrogen Receptor-Mediated Transactivation. | 2016 |
1 |
| 13 |
25706943 | SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatment. | 2015 |
3 |
| 14 |
24919713 | A771726, an anti-inflammatory drug, exerts an anticancer effect and reverses tamoxifen resistance in endocrine-resistant breast cancer cells. | 2014 Aug |
1 |
| 15 |
23810013 | ADAM22 as a prognostic and therapeutic drug target in the treatment of endocrine-resistant breast cancer. | 2013 |
1 |
| 16 |
21509526 | KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer. | 2012 Apr |
1 |
| 17 |
22134837 | Shorter disease-specific survival of ER-positive breast cancer patients with high cytoplasmic Src kinase expression after tamoxifen treatment. | 2012 Feb |
1 |
| 18 |
23951498 | A SNP in SRC-1 reduces bone density in tamoxifen-treated women. | 2012 |
1 |
| 19 |
21059860 | Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line. | 2011 Feb |
2 |
| 20 |
21175263 | Ubiquitin ligase c-Cbl is involved in tamoxifen-induced apoptosis of MCF-7 cells by downregulating the survival signals. | 2011 Jun |
2 |
| 21 |
19698761 | Identification of novel ER-alpha target genes in breast cancer cells: gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17beta-estradiol and tamoxifen. | 2010 Jan 15 |
1 |
| 22 |
20525379 | Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin. | 2010 |
1 |
| 23 |
18493848 | Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells. | 2009 May |
3 |
| 24 |
19026486 | Mislocalization of cell-cell adhesion complexes in tamoxifen-resistant breast cancer cells with elevated c-Src tyrosine kinase activity. | 2009 Mar 18 |
4 |
| 25 |
19138696 | Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells. | 2009 Jul |
1 |
| 26 |
19276281 | Coassociation of estrogen receptor and p160 proteins predicts resistance to endocrine treatment; SRC-1 is an independent predictor of breast cancer recurrence. | 2009 Mar 15 |
1 |
| 27 |
19830888 | Elevated Src kinase activity attenuates Tamoxifen response in vitro and is associated with poor prognosis clinically. | 2009 Aug |
6 |
| 28 |
18550772 | Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells. | 2008 Aug |
1 |
| 29 |
18583420 | ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells. | 2008 Oct |
1 |
| 30 |
19018258 | Phosphorylated c-Src in the nucleus is associated with improved patient outcome in ER-positive breast cancer. | 2008 Dec 2 |
1 |
| 31 |
17186241 | Targeting c-Src kinase enhances tamoxifen's inhibitory effect on cell growth by modulating expression of cell cycle and survival proteins. | 2007 Sep |
2 |
| 32 |
17254967 | p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2. | 2007 Jan 26 |
2 |
| 33 |
17283173 | Long-term treatment with tamoxifen facilitates translocation of estrogen receptor alpha out of the nucleus and enhances its interaction with EGFR in MCF-7 breast cancer cells. | 2007 Feb 1 |
1 |
| 34 |
17394086 | Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells. | 2007 |
1 |
| 35 |
17616457 | Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells. | 2007 Aug-Sep |
1 |
| 36 |
17627277 | PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1. | 2007 Aug 8 |
2 |
| 37 |
17631495 | Coactivators PGC-1beta and SRC-1 interact functionally to promote the agonist activity of the selective estrogen receptor modulator tamoxifen. | 2007 Sep 14 |
3 |
| 38 |
16333527 | Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells. | 2006 Jun |
2 |
| 39 |
16412380 | Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer. | 2006 Mar 3 |
4 |
| 40 |
16799644 | Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway. | 2006 Dec 7 |
5 |
| 41 |
16849545 | Physical and functional interactions between Cas and c-Src induce tamoxifen resistance of breast cancer cells through pathways involving epidermal growth factor receptor and signal transducer and activator of transcription 5b. | 2006 Jul 15 |
4 |
| 42 |
17172405 | Cooperative action of tamoxifen and c-Src inhibition in preventing the growth of estrogen receptor-positive human breast cancer cells. | 2006 Dec |
1 |
| 43 |
15528270 | The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity. | 2005 Mar |
8 |
| 44 |
11145737 | Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway. | 2001 Jan |
2 |