Protein Name epiregulin
Organism Homo sapiens
Gene ID 2069
Gene Symbol


UniProt O14944 (EREG_HUMAN)
Relationships Total Number of functionally related compound(s) : 498
Total Number of Articles : 566


Gene Summary

This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, the encoded protein may promote the progression of cancers of various human tissues. [provided by RefSeq, Jul 2015]

  • proepiregulin
  • EPR
  • ER
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