Tamoxifen

mitogen-activated protein kinase 3 ; Homo sapiens







43 Article(s)
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1 35054486 Overexpression of BQ323636.1 Modulated AR/IL-8/CXCR1 Axis to Confer Tamoxifen Resistance in ER-Positive Breast Cancer. 2022 Jan 10 1
2 32021441 ERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway. 2020 1
3 33081566 Tumor-associated macrophages promote human hepatoma Huh-7 cell migration and invasion through the Gli2/IGF-II/ERK1/2 axis by secreting TGF-β1. 2020 Nov 1 2
4 31592660 An AND-Gated Drug and Photoactivatable Cre-loxP System for Spatiotemporal Control in Cell-Based Therapeutics. 2019 Oct 18 1
5 29589904 Engineering a Dual Small Molecule Gated ZAP70 Switch in T Cells. 2018 Apr 20 1
6 29945962 Loss of Estrogen-Regulated MIR135A1 at 3p21.1 Promotes Tamoxifen Resistance in Breast Cancer. 2018 Sep 1 1
7 28026072 Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells. 2017 Apr 1
8 28423577 The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance. 2017 Apr 4 1
9 28855706 Chondrogenesis and osteogenesis are one continuous developmental and lineage defined biological process. 2017 Aug 30 1
10 27378269 Systematic drug screening reveals specific vulnerabilities and co-resistance patterns in endocrine-resistant breast cancer. 2016 Jul 4 1
11 25727020 Omega-3 free fatty acids inhibit tamoxifen-induced cell apoptosis. 2015 Apr 3 3
12 25846733 ObRb downregulation increases breast cancer cell sensitivity to tamoxifen. 2015 Sep 1
13 26096876 Tamoxifen Inhibits TGF-β-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2. 2015 Dec 2
14 26487496 Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer. 2015 Nov 1
15 26909308 A human beta cell line with drug inducible excision of immortalizing transgenes. 2015 Dec 1
16 24447434 Phosphorylated p-70S6K predicts tamoxifen resistance in postmenopausal breast cancer patients randomized between adjuvant tamoxifen versus no systemic treatment. 2014 Jan 21 1
17 24481325 GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts. 2014 Apr 2
18 24658355 Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity. 2014 Feb 28 1
19 24874276 GPER mediates enhanced cell viability and motility via non-genomic signaling induced by 17β-estradiol in triple-negative breast cancer cells. 2014 Sep 2
20 25085753 ERK1/2 is related to oestrogen receptor and predicts outcome in hormone-treated breast cancer. 2014 Aug 2
21 23338782 Dose-dependent effect of tamoxifen in tamoxifen-resistant breast cancer cells via stimulation by the ERK1/2 and AKT signaling pathways. 2013 Apr 3
22 23843844 Leptin as a potential target for estrogen receptor-positive breast cancer. 2013 Jun 1
23 22279179 Reprogramming of TAM toward proimmunogenic type through regulation of MAP kinases using a redox-active copper chelate. 2012 Apr 1
24 22427054 Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells. 2012 Jun 2
25 23086641 [Effect of Evn-50 on cell growth and apoptosis in tamoxifen-resistance human breast cancer cell line MCF-7/TAM-R]. 2012 Sep 4
26 21175263 Ubiquitin ligase c-Cbl is involved in tamoxifen-induced apoptosis of MCF-7 cells by downregulating the survival signals. 2011 Jun 2
27 21256460 A novel role for tamoxifen in the inhibition of human platelets. 2011 Feb 3
28 21720253 Crosstalk between estrogen receptor and mitogen-activated protein kinase signaling in the development and progression of endometrial cancer. 2011 Nov 1
29 20889557 High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients. 2010 Nov 1
30 19115248 Effect of tamoxifen and retinoic acid on bradykinin induced proliferation in MCF-7 cells. 2009 Feb 15 2
31 19544110 Activated PKCalpha/ERK1/2 signaling inhibits tamoxifen-induced apoptosis in C6 cells. 2009 Aug 2
32 17363451 Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen. 2007 Jun 4
33 16261397 Bidirectional cross talk between ERalpha and EGFR signalling pathways regulates tamoxifen-resistant growth. 2006 Mar 1
34 16455819 Activation function-1 domain of estrogen receptor regulates the agonistic and antagonistic actions of tamoxifen. 2006 May 7
35 16603346 Activated ERK1/2 and phosphorylated oestrogen receptor alpha are associated with improved breast cancer survival in women treated with tamoxifen. 2006 May 2
36 16740736 Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. 2006 Jun 1 5
37 15502196 Targeted somatic mutagenesis in the mouse epidermis. 2005 2
38 15806151 ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. 2005 Jun 23 1
39 15173068 Human epidermal growth factor receptor 2 status modulates subcellular localization of and interaction with estrogen receptor alpha in breast cancer cells. 2004 Jun 1 1
40 14531500 Oestrogen receptor-mediated modulation of the EGFR/MAPK pathway in tamoxifen-resistant MCF-7 cells. 2003 Sep 1
41 11773440 Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. 2002 Jan 1
42 12060612 Activated mitogen-activated protein kinase expression during human breast tumorigenesis and breast cancer progression. 2002 Jun 1
43 9372245 CGP 41251 and tamoxifen selectively inhibit mitogen-activated protein kinase activation and c-Fos phosphoprotein induction by substance P in human astrocytoma cells. 1997 Nov 1