Protein Name progesterone receptor
Organism Rattus norvegicus
Gene ID 25154
Gene Symbol

Pgr

UniProt Q63449 (PRGR_RAT)
Relationships Total Number of functionally related compound(s) : 237
Total Number of Articles : 340
Description

progesterone receptor

Gene Summary

Enables several functions, including nuclear steroid receptor activity; sequence-specific DNA binding activity; and steroid binding activity. Involved in several processes, including cellular response to estrogen stimulus; cellular response to gonadotropin stimulus; and regulation of DNA-templated transcription. Located in axon terminus; dendritic spine; and perikaryon. Biomarker of endometriosis and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in endometriosis; hyperprolactinemia; and obesity. Orthologous to human PGR (progesterone receptor). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • progesterone receptor
  • PR
  • nuclear receptor subfamily 3 group C member 3
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Properties