Tamoxifen

cytochrome P450 family 4 subfamily F member 3 ; Homo sapiens







28 Article(s)
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1 29436156 Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. 2018 May 2
2 29479969 Detection of Cytochrome P450 Polymorphisms in Breast Cancer Patients May Impact on Tamoxifen Therapy 2018 Feb 26 3
3 26446141 Augmentation of Endoxifen Exposure in Tamoxifen-Treated Women Following SSRI Switch. 2016 Feb 2
4 26896706 Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism. 2016 Apr 13 2
5 27198207 Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1. 2016 Dec 3
6 25940823 Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen. 2015 Aug 2
7 26423799 Comparative metabolic study between two selective estrogen receptor modulators, toremifene and tamoxifen, in human liver microsomes. 2015 Oct 1
8 24265353 The rs1800716 variant in CYP2D6 is associated with an increased double endometrial thickness in postmenopausal women on tamoxifen. 2014 Jan 4
9 25114852 Impact of CYP2D*6 in the adjuvant treatment of breast cancer patients with tamoxifen. 2014 Aug 10 2
10 22041137 Pharmacogenomics of tamoxifen: roles of drug metabolizing enzymes and transporters. 2012 4
11 22617226 Effects of CYP induction by rifampicin on tamoxifen exposure. 2012 Jul 5
12 21226615 Pharmacogenetics of endocrine therapy for breast cancer. 2011 2
13 21750172 Functional polymorphisms in UDP-glucuronosyl transferases and recurrence in tamoxifen-treated breast cancer survivors. 2011 Sep 1
14 20052538 Orally administered endoxifen is a new therapeutic agent for breast cancer. 2010 Jul 2
15 20425602 CYP2D6 polymorphisms and tamoxifen metabolism: clinical relevance. 2010 Jan 2
16 20877451 CYP2D6 testing to predict response to tamoxifen in women with breast cancer: Pharmacogenomic. 2010 Sep 2 2
17 19574470 Pharmacogenomics of tamoxifen therapy. 2009 Oct 2
18 17434921 Association between CYP3A4 genotype and risk of endometrial cancer following tamoxifen use. 2007 Oct 2
19 18001838 Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. 2007 Dec 1
20 15596297 Polymorphisms in cytochrome P4503A5 (CYP3A5) may be associated with race and tumor characteristics, but not metabolism and side effects of tamoxifen in breast cancer patients. 2005 Jan 10 2
21 15111773 Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen. 2004 May 6
22 15159443 Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. 2004 Sep 1
23 14652237 Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. 2003 Dec 3 4
24 14678248 Oxidative metabolism of tamoxifen to Z-4-hydroxy-tamoxifen by cytochrome P450 isoforms: an appraisal of in vitro studies. 2003 Nov 1
25 12124303 Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen. 2002 Aug 2
26 9498238 Expression of cytochrome P450 genes encoding enzymes active in the metabolism of tamoxifen in human uterine endometrium. 1998 Feb 2
27 4004771 Quantification of cytochrome P-450-dependent cyclohexane hydroxylase activity in normal and neoplastic reproductive tissues. 1985 Apr 15 2
28 4061517 Cytochrome P-450 activity in human leiomyoma and normal myometrium. 1985 Nov 1 2