Tamoxifen

cytochrome P450 family 2 subfamily C member 19 ; Homo sapiens







24 Article(s)
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Pub. Year
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1 33432065 Effect of CYP2C19 genotypes on tamoxifen metabolism and early-breast cancer relapse. 2021 Jan 11 4
2 30786012 Factors Affecting Tamoxifen Metabolism in Patients With Breast Cancer: Preliminary Results of the French PHACS Study. 2019 Sep 1
3 29479969 Detection of Cytochrome P450 Polymorphisms in Breast Cancer Patients May Impact on Tamoxifen Therapy 2018 Feb 26 1
4 30022682 Effect of CYP2C19 and CYP2D6 genotype on tamoxifen treatment outcome indicates endogenous and exogenous interplay. 2018 Aug 1 3
5 28798474 CYP2C19*2 and CYP2C19*17 variants and effect of tamoxifen on breast cancer recurrence: Analysis of the International Tamoxifen Pharmacogenomics Consortium dataset. 2017 Aug 10 1
6 26799162 Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients. 2016 Jun 3
7 27198207 Multigene and Drug Interaction Approach for Tamoxifen Metabolite Patterns Reveals Possible Involvement of CYP2C9, CYP2C19, and ABCB1. 2016 Dec 2
8 25940823 Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen. 2015 Aug 1
9 25339025 Association of CYP2C19 polymorphisms with survival of breast cancer patients using tamoxifen: results of a meta- analysis. 2014 4
10 23604525 Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies. 2013 Jun 1
11 23736997 CYP2C19 2 predicts substantial tamoxifen benefit in postmenopausal breast cancer patients randomized between adjuvant tamoxifen and no systemic treatment. 2013 Jun 8
12 23776391 Association of CYP2D6 and CYP2C19 polymorphisms and disease-free survival of Thai post-menopausal breast cancer patients who received adjuvant tamoxifen. 2013 4
13 23781139 Influence of CYP2D6 polymorphisms on serum levels of tamoxifen metabolites in Spanish women with breast cancer. 2013 2
14 20309015 Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial. 2011 Apr 1
15 21185724 Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes. 2011 Apr 2
16 21480951 Impact of CYP2D6, CYP3A5, CYP2C9 and CYP2C19 polymorphisms on tamoxifen pharmacokinetics in Asian breast cancer patients. 2011 May 2
17 21830868 The CYP2C19*2 genotype predicts tamoxifen treatment outcome in advanced breast cancer patients. 2011 Aug 3
18 21906462 The clinical effectiveness and cost-effectiveness of genotyping for CYP2D6 for the management of women with breast cancer treated with tamoxifen: a systematic review. 2011 Sep 1
19 21961651 SULT1A1, CYP2C19 and disease-free survival in early breast cancer patients receiving tamoxifen. 2011 Nov 1
20 20565970 Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer. 2010 Jun 21 3
21 21047200 CYP2C19*2 polymorphism is associated with increased survival in breast cancer patients using tamoxifen. 2010 Oct 7
22 18024866 Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes. 2007 Nov 20 1
23 16550168 Cytochrome P450 pharmacogenetics and cancer. 2006 Mar 13 1
24 12419838 Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA. 2002 Nov 1