Tamoxifen

cyclin D1 ; Homo sapiens







48 Article(s)
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1 33275817 Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration-resistant prostate cancer. 2021 Apr 1
2 33519190 Paeoniflorin Sensitizes Breast Cancer Cells to Tamoxifen by Downregulating microRNA-15b via the FOXO1/CCND1/β-Catenin Axis. 2021 1
3 33708885 FEN1 is a prognostic biomarker for ER+ breast cancer and associated with tamoxifen resistance through the ERα/cyclin D1/Rb axis. 2021 Feb 4
4 33839437 The prognostic value of cyclin D1 in breast cancer patients treated with hormonal therapy: A pilot study. 2021 Jun 1
5 31975484 Overcoming tamoxifen resistance in oestrogen receptor-positive breast cancer using the novel thiosemicarbazone anti-cancer agent, DpC. 2020 May 1
6 32722075 Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. 2020 Jul 24 1
7 33050377 Significance of Targeting VEGFR-2 and Cyclin D1 in Luminal-A Breast Cancer. 2020 Oct 10 1
8 33139730 LncRNA DILA1 inhibits Cyclin D1 degradation and contributes to tamoxifen resistance in breast cancer. 2020 Nov 2 5
9 33177647 Coffee decoction enhances tamoxifen proapoptotic activity on MCF-7 cells. 2020 Nov 11 1
10 30467747 The modulatory role of low concentrations of bisphenol A on tamoxifen-induced proliferation and apoptosis in breast cancer cells. 2019 Jan 1
11 31742207 Inhibition of tamoxifen's therapeutic effects by emodin in estrogen receptor-positive breast cancer cell lines. 2019 Nov 1
12 28415819 Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells. 2017 May 2 6
13 27519631 Tamoxifen has a proliferative effect in endometrial carcinoma mediated via the GPER/EGFR/ERK/cyclin D1 pathway: A retrospective study and an in vitro study. 2016 Dec 5 1
14 25846733 ObRb downregulation increases breast cancer cell sensitivity to tamoxifen. 2015 Sep 1
15 23755153 The effect of antineoplastic drugs in a male spontaneous mammary tumor model. 2014 1
16 24563328 Expression profiling of breast cancer patients treated with tamoxifen: prognostic or predictive significance. 2014 Apr 1
17 23874806 Changes in the transcriptome of the human endometrial Ishikawa cancer cell line induced by estrogen, progesterone, tamoxifen, and mifepristone (RU486) as detected by RNA-sequencing. 2013 2
18 24367492 RSF1 and not cyclin D1 gene amplification may predict lack of benefit from adjuvant tamoxifen in high-risk pre-menopausal women in the MA.12 randomized clinical trial. 2013 2
19 22266527 Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice. 2012 Apr 1
20 22422660 Furanodiene enhances tamoxifen-induced growth inhibitory activity of ERa-positive breast cancer cells in a PPARγ independent manner. 2012 Aug 2
21 22475046 Effects of cyclin D1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study. 2012 Apr 4 4
22 19636701 Co-amplification of CCND1 and EMSY is associated with an adverse outcome in ER-positive tamoxifen-treated breast cancers. 2010 Jun 3
23 20010939 Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells. 2010 Jan 19 1
24 19584281 Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway. 2009 Jul 15 1
25 18245487 Tamoxifen stimulates the growth of cyclin D1-overexpressing breast cancer cells by promoting the activation of signal transducer and activator of transcription 3. 2008 Feb 1 8
26 18280643 Free circulating mRNA in plasma from breast cancer patients and clinical outcome. 2008 May 18 1
27 18347178 Cyclin D1 expression in breast cancer patients receiving adjuvant tamoxifen-based therapy. 2008 Mar 15 3
28 18393977 Genetic alterations of CCND1 and EMSY in breast cancers. 2008 May 1
29 18823530 Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer. 2008 2
30 19202962 [Factors predicting failure of adjuvant hormonotherapy of breast carcinoma. A study in tamoxifen treated patients]. 2008 1
31 17486065 Amplification of CCND1 and PAK1 as predictors of recurrence and tamoxifen resistance in postmenopausal breast cancer. 2007 Oct 25 2
32 17593037 Cyclin D-1, interleukin-6, HER-2/neu, transforming growth factor receptor-II and prediction of relapse in women with early stage, hormone receptor-positive breast cancer treated with tamoxifen. 2007 Jul-Aug 1
33 17640162 Dietary flaxseed interaction with tamoxifen induced tumor regression in athymic mice with MCF-7 xenografts by downregulating the expression of estrogen related gene products and signal transduction pathways. 2007 2
34 16705121 Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients. 2006 May 17 1
35 16740736 Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. 2006 Jun 1 1
36 17145896 Cyclin D1 is necessary for tamoxifen-induced cell cycle progression in human breast cancer cells. 2006 Dec 1 7
37 15868442 Role of cyclin D1 in ErbB2-positive breast cancer and tamoxifen resistance. 2005 May 3
38 16140974 Adverse effect of adjuvant tamoxifen in premenopausal breast cancer with cyclin D1 gene amplification. 2005 Sep 1 4
39 15138474 A prognostic index for operable, node-negative breast cancer. 2004 May 17 1
40 15138475 Cyclin D1 overexpression is a negative predictive factor for tamoxifen response in postmenopausal breast cancer patients. 2004 May 17 3
41 15544931 Cyclin D1 expression is dependent on estrogen receptor function in tamoxifen-resistant breast cancer cells. 2004 Sep 7
42 15585645 Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines. 2004 Dec 1 2
43 12469160 Cyclin D1 expression and patient outcome after tamoxifen therapy in estrogen receptor positive metastatic breast cancer. 2003 Jan-Feb 3
44 12612058 Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells. 2003 Feb 2
45 10661763 Characterization of a human melanoma cell line with non-oestrogen receptor dependent tamoxifen resistance. 1999 Dec 1
46 9199341 Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution. 1997 Jul 1
47 9815758 Inducible overexpression of cyclin D1 in breast cancer cells reverses the growth-inhibitory effects of antiestrogens. 1997 Jun 1
48 7585469 Growth arrest associated changes of mRNA levels in breast cancer cells measured by semi-quantitative RT-PCR: potential early indicators of treatment response. 1995 Oct 20 1