Protein Name gonadotropin releasing hormone 1
Organism Homo sapiens
Gene ID 2796
Gene Symbol


UniProt P01148 (GON1_HUMAN)
Relationships Total Number of functionally related compound(s) : 1184
Total Number of Articles : 3207

gonadotropin releasing hormone 1

Gene Summary

This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]

  • progonadoliberin-1
  • GnRH-associated peptide 1
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
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