Tamoxifen

nuclear receptor corepressor 2 ; Homo sapiens







24 Article(s)
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1 35054486 Overexpression of BQ323636.1 Modulated AR/IL-8/CXCR1 Axis to Confer Tamoxifen Resistance in ER-Positive Breast Cancer. 2022 Jan 10 2
2 33806019 Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer. 2021 Mar 25 1
3 34709749 KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer. 2021 Oct 1
4 32110852 A Splice Variant of NCOR2, BQ323636.1, Confers Chemoresistance in Breast Cancer by Altering the Activity of NRF2. 2020 Feb 26 1
5 31120927 Norcantharidin regulates ERα signaling and tamoxifen resistance via targeting miR-873/CDK3 in breast cancer cells. 2019 1
6 29674510 Tamoxifen Resistance Trumped and Oral Selective Estrogen Receptor Degraders Arrive. 2018 Aug 1 2
7 23117886 SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ERα transcriptional activity. 2013 Jan 1 8
8 22249258 Targeting of the adaptor protein Tab2 as a novel approach to revert tamoxifen resistance in breast cancer cells. 2012 Oct 4 2
9 23015261 Elevated nuclear expression of the SMRT corepressor in breast cancer is associated with earlier tumor recurrence. 2012 Nov 4
10 19698761 Identification of novel ER-alpha target genes in breast cancer cells: gene- and cell-selective co-regulator recruitment at target promoters determines the response to 17beta-estradiol and tamoxifen. 2010 Jan 15 1
11 20406620 Inhibition of MAP kinase promotes the recruitment of corepressor SMRT by tamoxifen-bound estrogen receptor alpha and potentiates tamoxifen action in MCF-7 cells. 2010 May 28 4
12 19269830 Pinning down HER2-ER crosstalk in SMRT regulation. 2009 Apr 2
13 19858209 G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation. 2009 Dec 25 1
14 18546531 [Expression of ER alpha and SMRT in apoptosis of breast cancer cells induced by tamoxifen]. 2008 May 6
15 18838553 Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT. 2008 Oct 6 1
16 17591692 The silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) corepressor is required for full estrogen receptor alpha transcriptional activity. 2007 Sep 1
17 17599049 Estrogen-induced and TAFII30-mediated gene repression by direct recruitment of the estrogen receptor and co-repressors to the core promoter and its reversal by tamoxifen. 2007 Dec 13 1
18 15802375 Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. 2005 Jun 6
19 12738788 Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells. 2003 Jul 18 1
20 12145334 Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. 2002 Aug 4
21 11553641 The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes. 2001 Nov 16 3
22 11916237 Inhibition of erbB receptor (HER) tyrosine kinases as a strategy to abrogate antiestrogen resistance in human breast cancer. 2001 Dec 1
23 10589759 Expression of nuclear receptor interacting proteins TIF-1, SUG-1, receptor interacting protein 140, and corepressor SMRT in tamoxifen-resistant breast cancer. 1999 Nov 1
24 9171233 The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. 1997 Jun 1