Protein Name progesterone receptor
Organism Homo sapiens
Gene ID 5241
Gene Symbol

PGR

UniProt P06401 (PRGR_HUMAN)
Relationships Total Number of functionally related compound(s) : 863
Total Number of Articles : 1766
Description

progesterone receptor

Gene Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

synonyms
  • progesterone receptor
  • nuclear receptor subfamily 3 group C member 3
  • NR3C3
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Properties