Protein Name cytochrome P450 family 2 subfamily C member 19
Organism Homo sapiens
Gene ID 1557
Gene Symbol


UniProt P33261 (CP2CJ_HUMAN)
Relationships Total Number of functionally related compound(s) : 1098
Total Number of Articles : 2680

cytochrome P450 family 2 subfamily C member 19

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

  • cytochrome P450 2C19
  • (R)-limonene 6-monooxygenase
  • (S)-limonene 6-monooxygenase
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