| Protein Name | sex hormone binding globulin |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6462 |
| Gene Symbol | SHBG |
| UniProt | P04278 (SHBG_HUMAN), I3L145 (I3L145_HUMAN), B4DYU0 (B4DYU0_HUMAN), B0FWH2 (B0FWH2_HUMAN), B0FWH8 (B0FWH8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
621
Total Number of Articles : 1747 |
Description |
sex hormone binding globulin |
| Gene Summary |
This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
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| Properties | |