Tamoxifen

BCL2 apoptosis regulator ; Homo sapiens







72 Article(s)
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1 35154350 Paeoniflorin Enhances the Sensitivity of ER-Positive Breast Cancer Cells to Tamoxifen through Promoting Sirtuin 4. 2022 1
2 34349560 Long Non-Coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis [Retraction]. 2021 1
3 34697301 Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer. 2021 Oct 25 1
4 32210618 Long Non-coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis. 2020 1
5 32215462 Immunohistochemical assessment of symptomatic postmenopausal endometrial polyps in tamoxifen users and nonusers: a case control study. 2020 Jan-Feb 1
6 32722075 Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells. 2020 Jul 24 2
7 33083299 Synergistic Effects of Lauryl Gallate and Tamoxifen on Human Breast Cancer Cell. 2020 Jul 1
8 28431397 Sensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damages. 2017 Apr 25 1
9 28646740 Epigallocatechin-3-gallate promotes apoptosis in human breast cancer T47D cells through down-regulation of PI3K/AKT and Telomerase. 2017 Oct 2
10 28869838 FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ERα-Positive Breast Cancer Cells. 2017 Oct 1
11 26697130 Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells. 2016 1
12 27664187 Tamoxifen citrate-loaded poly(d,l) lactic acid nanoparticles: Evaluation for their anticancer activity in vitro and in vivo. 2016 Nov 1
13 25539992 Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. 2015 Apr 2
14 25848915 Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression. 2015 Feb 25 4
15 26109525 Tamoxifen-Induced Cell Death of Malignant Glioma Cells Is Brought About by Oxidative-Stress-Mediated Alterations in the Expression of BCL2 Family Members and Is Enhanced on miR-21 Inhibition. 2015 Oct 3
16 26397135 E2F7 overexpression leads to tamoxifen resistance in breast cancer cells by competing with E2F1 at miR-15a/16 promoter. 2015 Oct 13 3
17 26472348 Differences in clinical importance of Bcl-2 in breast cancer according to hormone receptors status or adjuvant endocrine therapy. 2015 Oct 15 1
18 23755153 The effect of antineoplastic drugs in a male spontaneous mammary tumor model. 2014 1
19 24612549 Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma. 2014 Mar 11 1
20 24841429 Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (review). 2014 Jul 1
21 25081647 Evaluation of the ability of adjuvant tamoxifen-benefit gene signatures to predict outcome of hormone-naive estrogen receptor-positive breast cancer patients treated with tamoxifen in the advanced setting. 2014 Dec 1
22 23342080 Gene expression signatures that predict outcome of tamoxifen-treated estrogen receptor-positive, high-risk, primary breast cancer patients: a DBCG study. 2013 1
23 23609470 Estrogen receptor α is the major driving factor for growth in tamoxifen-resistant breast cancer and supported by HER/ERK signaling. 2013 May 1
24 23688426 Novel tamoxifen derivative Ridaifen-B induces Bcl-2 independent autophagy without estrogen receptor involvement. 2013 Jun 14 1
25 23845438 BCL-2: a new therapeutic target in estrogen receptor-positive breast cancer? 2013 Jul 8 1
26 24172207 Priming BCL-2 to kill: the combination therapy of tamoxifen and ABT-199 in ER+ breast cancer. 2013 2
27 22961366 Carboplatin treatment of antiestrogen-resistant breast cancer cells. 2012 Nov 3
28 21826535 A five-gene model predicts clinical outcome in ER+/PR+, early-stage breast cancers treated with adjuvant tamoxifen. 2011 Oct 1
29 19757172 The growth-inhibition effect of tamoxifen in the combination chemotherapeutics on the human cholangiocarcinoma cell line QBC939. 2010 Jul 1
30 20305694 Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma. 2010 Jun 3 1
31 20876285 Oncogenic HER2{Delta}16 suppresses miR-15a/16 and deregulates BCL-2 to promote endocrine resistance of breast tumors. 2010 Dec 9
32 19002577 Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ERalpha. 2009 Dec 2
33 19029119 Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy. 2009 Jan 30 1
34 19115248 Effect of tamoxifen and retinoic acid on bradykinin induced proliferation in MCF-7 cells. 2009 Feb 15 2
35 19173092 An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer. 2009 1
36 19337026 Ceramide-induced autophagy: to junk or to protect cells? 2009 May 1
37 19661335 Keratinocyte growth factor (KGF) regulates estrogen receptor-alpha (ER-alpha) expression and cell apoptosis via phosphatidylinositol 3-kinase (PI3K)/Akt pathway in human breast cancer cells. 2009 Aug 1
38 18676864 The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis. 2008 Aug 1 1
39 18928543 A candidate molecular signature associated with tamoxifen failure in primary breast cancer. 2008 1
40 17046747 Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer. 2007 Feb 2
41 17629615 Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT. 2007 Oct 28 1
42 16413707 Does tamoxifen therapy affect the hormone receptor expression and cell proliferation indices of endometrial polyps? An immunohistochemical comparison of endometrial polyps from postmenopausal women exposed and not exposed to tamoxifen. 2006 Jun 20 1
43 16854582 Effect of keratinocyte growth factor on cell viability in primary cultured human prostate cancer stromal cells. 2006 Jul 1
44 16974115 Expression of Bcl-2 and Ki-67 in tamoxifen-associated endometrial polyps: comparison with postmenopausal polyps. 2006 Sep 3
45 15606891 Activated JNK brings about accelerated apoptosis of Bcl-2-overexpressing C6 glioma cells on treatment with tamoxifen. 2005 Jan 5
46 15830342 Modulation of tamoxifen sensitivity by antisense Bcl-2 and trastuzumab in breast carcinoma cells. 2005 May 15 3
47 16267611 Morphologic and immunophenotypic markers as surrogate endpoints of tamoxifen effect for prevention of breast cancer. 2005 Dec 1
48 14996734 PC cell-derived growth factor mediates tamoxifen resistance and promotes tumor growth of human breast cancer cells. 2004 Mar 1 1
49 15138474 A prognostic index for operable, node-negative breast cancer. 2004 May 17 1
50 15513900 Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells. 2004 Dec 1