Tamoxifen

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







237 Article(s)
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1 35144966 Breast Cancer Index Is a Predictive Biomarker of Treatment Benefit and Outcome from Extended Tamoxifen Therapy: Final Analysis of the Trans-aTTom Study. 2022 May 2 1
2 33258078 Predictive role of HER2-status on the effectiveness of endocrine adjuvant treatment in postmenopausal breast cancer patients: a population-based cohort study. 2021 Apr 1
3 33332933 Implications of Tamoxifen Resistance in Palbociclib Efficacy for Patients with Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: Subgroup Analyses of KCSG-BR15-10 (YoungPEARL). 2021 Jul 1
4 33682068 Evaluating human epidermal growth factor receptor 2 roles in the efficacy of Tamoxifen treatment in breast cancer, a systematic review. 2021 Apr 8
5 33800852 Fatty Acid Synthase Confers Tamoxifen Resistance to ER+/HER2+ Breast Cancer. 2021 Mar 6 2
6 33833890 Suicidality and Illness Course Worsening in a Male Patient with Bipolar Disorder during Tamoxifen Treatment for ER+/HER2+ Breast Cancer. 2021 2
7 33905134 Final results of the randomized phase 2 LEO trial and bone protective effects of everolimus for premenopausal hormone receptor-positive, HER2-negative metastatic breast cancer. 2021 Apr 27 1
8 34058187 Tamoxifen overcomes the trastuzumab-resistance of SK-BR-3 tumorspheres by targeting crosstalk between cytoplasmic estrogen receptor α and the EGFR/HER2 signaling pathway. 2021 Aug 2
9 34190995 Assessment of 25-Year Survival of Women With Estrogen Receptor-Positive/ERBB2-Negative Breast Cancer Treated With and Without Tamoxifen Therapy: A Secondary Analysis of Data From the Stockholm Tamoxifen Randomized Clinical Trial. 2021 Jun 1 1
10 31618131 Absolute Improvements in Freedom From Distant Recurrence to Tailor Adjuvant Endocrine Therapies for Premenopausal Women: Results From TEXT and SOFT. 2020 Apr 20 2
11 32352244 Buparlisib in combination with tamoxifen in pretreated patients with hormone receptor-positive, HER2-negative advanced breast cancer molecularly stratified for PIK3CA mutations and loss of PTEN expression. 2020 Jul 1
12 32690611 A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer. 2020 Oct 9 3
13 32756099 Case report: 5-year progression free survival and complete liver response in a patient with metastatic breast cancer treated with everolimus plus exemestane. 2020 Jul 31 1
14 32843722 The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen. 2020 Oct 2
15 33052961 HER2-mediated enhancement of Ebola virus entry. 2020 Oct 1
16 30531871 Acquired HER2 mutations in ER+ metastatic breast cancer confer resistance to estrogen receptor-directed therapies. 2019 Feb 1
17 31183434 Lipoproteins modulate growth and P-glycoprotein expression in drug-resistant HER2-overexpressed breast cancer cells. 2019 Apr 1
18 31932263 Quantitative assessment of CD68+ AND CD163+ macrophages in the primary focus and metastatic lesions of regional lymph nodes in non-luminal her2-positive invasive breast carcinoma 2019 Oct 31 1
19 28786348 Clinical Evidence on the Magnitude of Change in Growth Pathway Activity in Relation to Tamoxifen Resistance is Required. 2018 2
20 29383628 Tamoxifen therapy improves overall survival in luminal A subtype of ductal carcinoma in situ: a study based on nationwide Korean Breast Cancer Registry database. 2018 Jun 1
21 29720121 C-Cbl reverses HER2-mediated tamoxifen resistance in human breast cancer cells. 2018 May 2 7
22 29940172 Appraising the "entourage effect": Antitumor action of a pure cannabinoid versus a botanical drug preparation in preclinical models of breast cancer. 2018 Nov 1
23 30358233 Should addition of five years of ovarian suppression to tamoxifen be "must" for hormone receptor positive and HER-2 positive breast cancer under the age of 35? 2018 Jul-Aug 1
24 30458882 HER4 expression in estrogen receptor-positive breast cancer is associated with decreased sensitivity to tamoxifen treatment and reduced overall survival of postmenopausal women. 2018 Nov 20 1
25 30583472 Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy. 2018 Dec 21 2
26 31149534 Tamoxifen withdrawal in women with progressive metastatic breast cancer: a case series of six patients. 2018 Oct 2
27 27137076 Breast Cancer: Current Molecular Therapeutic Targets and New Players. 2017 1
28 27721408 Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance. 2017 Apr 1
29 27879270 Breast Cancer Resistance to Antiestrogens Is Enhanced by Increased ER Degradation and ERBB2 Expression. 2017 Jan 15 2
30 27942916 Synergistic disruption of ERα/HER2 crosstalk by endoxifen and lapatinib in breast cancer cells. 2017 Jan 5
31 27966906 Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles. 2017 Jan 24 1
32 28100469 Immunohistochemical Phenotype of Breast Cancer during 25-Year Follow-up of the Royal Marsden Tamoxifen Prevention Trial. 2017 Mar 1
33 28416639 Absent progesterone receptor expression in the lymph node metastases of ER-positive, HER2-negative breast cancer is associated with relapse on tamoxifen. 2017 Nov 1
34 28494403 HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2. 2017 Jul 7
35 28498399 Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells. 2017 Jun 2
36 28601930 Survival improvement in hormone-responsive young breast cancer patients with endocrine therapy. 2017 Sep 1
37 28637868 Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells. 2017 Aug 18 4
38 28881721 Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer. 2017 Aug 8 5
39 29760748 Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables. 2017 Winter 1
40 26581908 Anti-cancer effect of metformin by suppressing signaling pathway of HER2 and HER3 in tamoxifen-resistant breast cancer cells. 2016 May 2
41 26662961 The effects of bufadienolides on HER2 overexpressing breast cancer cells. 2016 Jun 3
42 26771508 HER2 Targeted Breast Cancer Therapy with Switchable "Off/On" Multifunctional "Smart" Magnetic Polymer Core-Shell Nanocomposites. 2016 Jan 27 2
43 26792291 A Retrospective Study on the Efficacy of Trastuzumab in HER2-Positive and Tamoxifen-Refractory Breast Cancer with Brain Metastasis. 2016 Feb 1
44 26803986 HOX genes: Major actors in resistance to selective endocrine response modifiers. 2016 Apr 1
45 26884313 Roles of the ER-α36-EGFR/HER2 positive regulatory loops in tamoxifen resistance. 2016 Jul 5
46 26959415 Prior Adjuvant Tamoxifen Treatment in Breast Cancer Is Linked to Increased AIB1 and HER2 Expression in Metachronous Contralateral Breast Cancer. 2016 2
47 27044936 Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early Breast Cancer: TEXT and SOFT Trials. 2016 Jul 1 1
48 27573917 NK cell-mediated antibody-dependent cellular cytotoxicity is enhanced by tamoxifen in HER2/neu non-amplified, but not HER2/neu-amplified, breast cancer cells. 2016 Nov 5
49 27695927 Erratum to: NK cell-mediated antibody-dependent cellular cytotoxicity is enhanced by tamoxifen in HER2/neu non-amplified, but not HER2/neu-amplified, breast cancer cells. 2016 Nov 2
50 23479208 Ki-67 evaluation at the hottest spot predicts clinical outcome of patients with hormone receptor-positive/HER2-negative breast cancer treated with adjuvant tamoxifen monotherapy. 2015 Jan 1