Tamoxifen

epidermal growth factor receptor ; Homo sapiens







120 Article(s)
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1 35337112 Investigation of the Antitumor Effects of Tamoxifen and Its Ferrocene-Linked Derivatives on Pancreatic and Breast Cancer Cell Lines. 2022 Mar 5 1
2 35445730 EGFR inhibition reverses epithelial‑mesenchymal transition, and decreases tamoxifen resistance via Snail and Twist downregulation in breast cancer cells. 2022 Jun 5
3 35559420 YY1 as a promoter regulating the circ_0001946/miR-671-5p/EGFR axis to promote chemotherapy resistance in breast cancer cells. 2022 1
4 33508166 Investigating differences between tamoxifen resistant and sensitive breast cancer cells with flow cytometry. 2021 Feb 2
5 33691171 A pan-cancer analysis of the HER family gene and their association with prognosis, tumor microenvironment, and therapeutic targets. 2021 May 15 1
6 34006822 Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization. 2021 May 18 1
7 34058187 Tamoxifen overcomes the trastuzumab-resistance of SK-BR-3 tumorspheres by targeting crosstalk between cytoplasmic estrogen receptor α and the EGFR/HER2 signaling pathway. 2021 Aug 1
8 34407787 Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells. 2021 Aug 18 2
9 32021441 ERα36 as a Potential Therapeutic Target for Tamoxifen-Resistant Breast Cancer Cell Line Through EGFR/ERK Signaling Pathway. 2020 1
10 33046784 Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells. 2020 Oct 12 1
11 30189107 PTPH1 immunohistochemical expression and promoter methylation in breast cancer patients from India: A retrospective study. 2019 Feb 1
12 31088266 Colon Cancer Cell Secretes EGF to Promote M2 Polarization of TAM Through EGFR/PI3K/AKT/mTOR Pathway. 2019 Jan 1 1
13 31670920 EGFR is a Therapeutic Target in Hormone Receptor-Positive Breast Cancer. 2019 2
14 31821370 Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer. 2019 4
15 28786348 Clinical Evidence on the Magnitude of Change in Growth Pathway Activity in Relation to Tamoxifen Resistance is Required. 2018 1
16 29028222 Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer. 2018 Apr 1 2
17 29484139 S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB. 2018 Jan 26 1
18 29787277 Targeting of EGFR, VEGFR2, and Akt by Engineered Dual Drug Encapsulated Mesoporous Silica-Gold Nanoclusters Sensitizes Tamoxifen-Resistant Breast Cancer. 2018 Jul 2 1
19 30050469 Tamoxifen-Induced Apoptosis of MCF-7 Cells via GPR30/PI3K/MAPKs Interactions: Verification by ODE Modeling and RNA Sequencing. 2018 3
20 30140390 Correction: S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB. 2018 Jul 31 1
21 27225751 The distribution pattern of ERα expression, ESR1 genetic variation and expression of growth factor receptors: association with breast cancer prognosis in Russian patients treated with adjuvant tamoxifen. 2017 Aug 5
22 28100469 Immunohistochemical Phenotype of Breast Cancer during 25-Year Follow-up of the Royal Marsden Tamoxifen Prevention Trial. 2017 Mar 1
23 28231748 Aloe-Emodin Enhances Tamoxifen Cytotoxicity by Suppressing Ras/ERK and PI3K/mTOR in Breast Cancer Cells. 2017 1
24 28955730 TGF-β Stimulation of EMT Programs Elicits Non-genomic ER-α Activity and Anti-estrogen Resistance in Breast Cancer Cells. 2017 1
25 26581908 Anti-cancer effect of metformin by suppressing signaling pathway of HER2 and HER3 in tamoxifen-resistant breast cancer cells. 2016 May 2
26 26803986 HOX genes: Major actors in resistance to selective endocrine response modifiers. 2016 Apr 1
27 26884313 Roles of the ER-α36-EGFR/HER2 positive regulatory loops in tamoxifen resistance. 2016 Jul 5
28 27083550 Delineating the molecular mechanisms of tamoxifen's oncolytic actions in estrogen receptor-negative cancers. 2016 Jun 15 3
29 27494858 Dichloroacetate potentiates tamoxifen-induced cell death in breast cancer cells via downregulation of the epidermal growth factor receptor. 2016 Sep 13 4
30 27519631 Tamoxifen has a proliferative effect in endometrial carcinoma mediated via the GPER/EGFR/ERK/cyclin D1 pathway: A retrospective study and an in vitro study. 2016 Dec 5 1
31 25882671 Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion. 2015 1
32 25973295 Downregulation of ER-α36 expression sensitizes HER2 overexpressing breast cancer cells to tamoxifen. 2015 4
33 26166014 Differential effect of EGFR inhibitors on tamoxifen-resistant breast cancer cells. 2015 Sep 3
34 26238412 HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen. 2015 Oct 1
35 26487496 Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERα-positive breast cancer. 2015 Nov 5
36 26697525 A pivotal role for HOXB7 protein in endocrine resistant breast cancer. 2015 1
37 24414992 Tumor-associated macrophages are correlated with tamoxifen resistance in the postmenopausal breast cancer patients. 2014 Jul 2
38 24481325 GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts. 2014 Apr 2
39 24758408 Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation. 2014 Apr 23 1
40 24916398 Snail and Slug mediate tamoxifen resistance in breast cancer cells through activation of EGFR-ERK independent of epithelial-mesenchymal transition. 2014 Aug 1
41 25203051 Disruption of the ER-α36-EGFR/HER2 positive regulatory loops restores tamoxifen sensitivity in tamoxifen resistance breast cancer cells. 2014 6
42 23609470 Estrogen receptor α is the major driving factor for growth in tamoxifen-resistant breast cancer and supported by HER/ERK signaling. 2013 May 2
43 24091623 Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial. 2013 Oct 29 2
44 21690342 The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. 2012 Feb 21 3
45 21935603 The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin. 2012 Jun 1
46 22808167 Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer. 2012 1
47 22922893 Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells. 2012 Nov 1
48 23039365 Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan. 2012 Oct 6 1
49 23273253 Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer. 2012 Dec 28 2
50 20133149 Adjuvant endocrine therapy in postmenopausal breast cancer patients: does hormone receptor status influence decision-making? 2011 Feb 1