Tamoxifen

insulin like growth factor 1 receptor ; Homo sapiens







41 Article(s)
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1 33508166 Investigating differences between tamoxifen resistant and sensitive breast cancer cells with flow cytometry. 2021 Feb 2
2 31490549 IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer. 2020 Apr 15 8
3 32435229 IGFBP-1 Expression Promotes Tamoxifen Resistance in Breast Cancer Cells via Erk Pathway Activation. 2020 2
4 29028222 Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer. 2018 Apr 1 2
5 29353882 IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer. 2018 Apr 2
6 28096479 IGF-1 Receptor Modulates FoxO1-Mediated Tamoxifen Response in Breast Cancer Cells. 2017 Apr 10
7 28468775 Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds. 2017 Jul 1
8 26706833 The influence of insulin-like Growth Factor-1-Receptor expression and endocrine treatment on clinical outcome of postmenopausal hormone receptor positive breast cancer patients: A Dutch TEAM substudy analysis. 2016 Apr 1
9 26803986 HOX genes: Major actors in resistance to selective endocrine response modifiers. 2016 Apr 1
10 27178332 ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling. 2016 Jun 2
11 25882671 Factors Promoting Tamoxifen Resistance in Breast Cancer via Stimulating Breast Cancer Stem Cell Expansion. 2015 1
12 23459444 Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen. 2014 Feb 2
13 24532107 Dynamics of IGF-1R expression during endocrine breast cancer treatment. 2014 Aug 1
14 25362932 Association between insulin-like growth factor-1 receptor (IGF1R) negativity and poor prognosis in a cohort of women with primary breast cancer. 2014 Nov 3 1
15 22573715 Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment. 2012 Jul 1 3
16 22835717 Clinico-pathologic comparison of type II endometrial cancers based on tamoxifen exposure. 2012 Nov 2
17 23074235 Targeting estrogen receptor-α reduces adrenocortical cancer (ACC) cell growth in vitro and in vivo: potential therapeutic role of selective estrogen receptor modulators (SERMs) for ACC treatment. 2012 Dec 1
18 20890664 Pasireotide, an IGF-I action inhibitor, prevents growth hormone and estradiol-induced mammary hyperplasia. 2011 Mar 1
19 21057462 Increased insulin-like growth factor-1 receptor mRNA expression predicts poor survival in immunophenotypes of early breast carcinoma. 2011 Feb 1
20 21273576 Measuring IGF-1, ER-α and EGFR expression can predict tamoxifen-resistance in ER-positive breast cancer. 2011 Jan 1
21 21595894 Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes. 2011 May 19 2
22 21734071 Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment. 2011 Oct 1
23 21939528 erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines. 2011 Sep 22 2
24 19002577 Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ERalpha. 2009 Dec 1
25 19138696 Estrogen signals via an extra-nuclear pathway involving IGF-1R and EGFR in tamoxifen-sensitive and -resistant breast cancer cells. 2009 Jul 1
26 19173092 An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer. 2009 1
27 19435893 Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer. 2009 May 15 1
28 18245484 Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function. 2008 Feb 1 3
29 18508432 The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance. 2008 May 1 1
30 18583420 ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells. 2008 Oct 1
31 18769129 Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells. 2008 Sep 1
32 19074892 Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. 2008 Dec 15 1
33 16037379 Insulin-like growth factor-I receptor signaling in tamoxifen-resistant breast cancer: a supporting role to the epidermal growth factor receptor. 2005 Nov 2
34 16113104 Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer. 2005 Jul 4
35 15072444 Tamoxifen modulation of etoposide cytotoxicity involves inhibition of protein kinase C activity and insulin-like growth factor II expression in brain tumor cells. 2004 Mar-Apr 1
36 10940491 Tamoxifen-induced cell death in malignant melanoma cells: possible involvement of the insulin-like growth factor-1 (IGF-1) pathway. 2000 Jul 25 6
37 10940495 Effect of tamoxifen treatment on the endometrial expression of human insulin-like growth factors and their receptor mRNAs. 2000 Jul 25 3
38 10070856 Altered expression of the IGF-1 receptor in a tamoxifen-resistant human breast cancer cell line. 1999 Feb 3
39 9205064 Tamoxifen interferes with the insulin-like growth factor I receptor (IGF-IR) signaling pathway in breast cancer cells. 1997 Jul 1 8
40 9142960 Insulin-like growth factors in breast cancer. 1996 1
41 8746077 Insulin-like growth factors and breast cancer. 1995 1