Bortezomib


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1406 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 166
2 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 105
3 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 84
4 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 73
5 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 73
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 66
7 phorbol-12-myristate-13-acetate-induced protein 1 APR_HUMAN PMAIP1 Homo sapiens 5366 357 53
8 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 51
9 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 45
10 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 43
11 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 39
12 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 38
13 NFKB inhibitor alpha IKBA_HUMAN NFKBIA Homo sapiens 4792 1043 36
14 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 35
15 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 32
16 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 29
17 heat shock protein family A (Hsp70) member 5 BIP_HUMAN HSPA5 Homo sapiens 3309 965 28
18 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 28
19 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 27
20 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 27
21 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 27
22 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 26
23 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 25
24 proteasome 20S subunit beta 5 PSB5_HUMAN PSMB5 Homo sapiens 5693 34 25
25 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 25
26 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 25
27 activating transcription factor 4 ATF4_HUMAN ATF4 Homo sapiens 468 451 24
28 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 24
29 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 23
30 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 23
31 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 22
32 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 21
33 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 21
34 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 20
35 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 19
36 X-box binding protein 1 XBP1_HUMAN XBP1 Homo sapiens 7494 350 18
37 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 17
38 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 17
39 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 16
40 neurensin 1 NRSN1_HUMAN NRSN1 Homo sapiens 140767 30 16
41 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 16
42 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 16
43 BCL2 like 11 B2L11_HUMAN BCL2L11 Homo sapiens 10018 399 16
44 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 15
45 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 15
46 X-linked inhibitor of apoptosis XIAP_HUMAN XIAP Homo sapiens 331 647 15
47 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 15
48 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 15
49 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 14
50 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 14