Protein Name interferon gamma
Organism Homo sapiens
Gene ID 3458
Gene Symbol

IFNG

UniProt P01579 (IFNG_HUMAN)
Relationships Total Number of functionally related compound(s) : 3371
Total Number of Articles : 8045
Description

interferon gamma

Gene Summary

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

synonyms
  • interferon gamma
  • IFN-gamma
  • immune interferon
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Properties