Protein Name annexin A5
Organism Homo sapiens
Gene ID 308
Gene Symbol

ANXA5

UniProt P08758 (ANXA5_HUMAN), V9HWE0 (V9HWE0_HUMAN)
Relationships Total Number of functionally related compound(s) : 1785
Total Number of Articles : 2964
Description

annexin A5

Gene Summary

The Annexin 5 gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. Polymorphisms in this gene have been implicated in various obstetric complications. [provided by RefSeq, Dec 2019]

synonyms
  • annexin A5
  • CBP-I
  • PAP-I
Click to show/hide the synonyms
Properties