Protein Name phorbol-12-myristate-13-acetate-induced protein 1
Organism Homo sapiens
Gene ID 5366
Gene Symbol


UniProt Q13794 (APR_HUMAN), A0A0S2Z490 (A0A0S2Z490_HUMAN)
Relationships Total Number of functionally related compound(s) : 357
Total Number of Articles : 486

phorbol-12-myristate-13-acetate-induced protein 1

Gene Summary

This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state. [provided by RefSeq, Aug 2020]

  • phorbol-12-myristate-13-acetate-induced protein 1
  • PMA-induced protein 1
  • adult T cell leukemia-derived PMA-responsive
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