| Protein Name | phorbol-12-myristate-13-acetate-induced protein 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5366 |
| Gene Symbol | PMAIP1 |
| UniProt | Q13794 (APR_HUMAN), A0A0S2Z490 (A0A0S2Z490_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
357
Total Number of Articles : 486 |
Description |
phorbol-12-myristate-13-acetate-induced protein 1 |
| Gene Summary |
This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state. [provided by RefSeq, Aug 2020] |
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| Properties | |