Bortezomib

cyclin dependent kinase inhibitor 1A ; Homo sapiens







26 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34025442 Proteasome Inhibition Suppresses KIT-Independent Gastrointestinal Stromal Tumors Via Targeting Hippo/YAP/Cyclin D1 Signaling. 2021 1
2 34837676 AntagomiR-19a Induced Better Responsiveness to Bortezomib in Myeloma Cell Lines. 2021 Oct 1
3 32628811 Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21Cip1 and p27Kip1. 2020 Aug 2
4 27926485 Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. 2017 Jan 10 2
5 26740054 Signaling mechanisms of bortezomib in TRAF3-deficient mouse B lymphoma and human multiple myeloma cells. 2016 Feb 2
6 26025442 Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment. 2015 May 30 1
7 24113592 Thermally targeted p21 peptide enhances bortezomib cytotoxicity in androgen-independent prostate cancer cell lines. 2014 Feb 2
8 25155625 Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines. 2014 Dec 2
9 22313636 Bortezomib induces apoptosis and growth suppression in human medulloblastoma cells, associated with inhibition of AKT and NF-ĸB signaling, and synergizes with an ERK inhibitor. 2012 Apr 1
10 22964432 Roles of estrogen receptor and p21(Waf1) in bortezomib-induced growth inhibition in human breast cancer cells. 2012 Nov 14
11 23055533 Antitumor effects of proteasome inhibition in anaplastic thyroid carcinoma. 2012 Nov 3
12 19960346 Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines. 2010 Aug 1
13 19041685 Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels. 2009 Mar 2
14 17522864 Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma. 2008 Apr 2
15 17786311 The mechanism of cross-resistance to proteasome inhibitor bortezomib and overcoming resistance in Ewing's family tumor cells. 2007 Oct 1
16 16928825 Bortezomib inhibits docetaxel-induced apoptosis via a p21-dependent mechanism in human prostate cancer cells. 2006 Aug 4
17 15929791 Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy. 2005 Jun 1 1
18 15930312 Bortezomib abolishes tumor necrosis factor-related apoptosis-inducing ligand resistance via a p21-dependent mechanism in human bladder and prostate cancer cells. 2005 Jun 1 6
19 15975933 Cleavage of p21/WAF1/CIP1 by proteinase 3 modulates differentiation of a monocytic cell line. Molecular analysis of the cleavage site. 2005 Aug 26 1
20 14965369 Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. 2004 Feb 3
21 15016328 Proteasome inhibitor PS-341 down-regulates prostate-specific antigen (PSA) and induces growth arrest and apoptosis of androgen-dependent human prostate cancer LNCaP cells. 2004 Mar 1
22 15197486 Effects of the proteasome inhibitor bortezomib alone and in combination with chemotherapy in the A549 non-small-cell lung cancer cell line. 2004 Oct 1
23 12631620 Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. 2003 Mar 2
24 12893773 The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. 2003 Nov 15 1
25 12943815 Schedule-dependent molecular effects of the proteasome inhibitor bortezomib and gemcitabine in pancreatic cancer. 2003 Jul 5
26 11400168 26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. 2001 Apr 2-27 3