CPRiL

RELA

RELA proto-oncogene, NF-kB subunit

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

• transcription factor p65
• NF-kappa-B p65delta3
• NF-kappa-B transcription factor p65
nuclear factor NF-kappa-B p65 subunit
nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
v-rel avian reticuloendotheliosis viral oncogene homolog A
AIF3BL3
CMCU
NFKB3
p65