Bortezomib

signal transducer and activator of transcription 3 ; Homo sapiens







20 Article(s)
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1 33572814 HDAC6-Selective Inhibitor Overcomes Bortezomib Resistance in Multiple Myeloma. 2021 Jan 29 2
2 34837676 AntagomiR-19a Induced Better Responsiveness to Bortezomib in Myeloma Cell Lines. 2021 Oct 1
3 32298237 Heme oxygenase-1 inhibition mediates Gas6 to enhance bortezomib-sensitivity in multiple myeloma via ERK/STAT3 axis. 2020 Apr 16 1
4 31337650 IL6 Promotes a STAT3-PRL3 Feedforward Loop via SHP2 Repression in Multiple Myeloma. 2019 Sep 15 3
5 31456939 Carnosol, a Natural Polyphenol, Inhibits Migration, Metastasis, and Tumor Growth of Breast Cancer via a ROS-Dependent Proteasome Degradation of STAT3. 2019 1
6 29899697 Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade. 2018 1
7 29914181 Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model. 2018 Jun 16 1
8 28000897 Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma. 2017 Feb 8
9 24407159 Dendritic cells loaded with myeloma cells pretreated with a combination of JSI-124 and bortezomib generate potent myeloma-specific cytotoxic T lymphocytes in vitro. 2014 Apr 3
10 24627094 Sequential treatment of HPV E6 and E7-expressing TC-1 cells with bortezomib and celecoxib promotes apoptosis through p-p38 MAPK-mediated downregulation of cyclin D1 and CDK2. 2014 May 2
11 24627483 Regulation of PSMB5 protein and β subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in bortezomib-mediated anticancer therapy. 2014 May 2 3
12 24824872 Bortezomib induces apoptosis by interacting with JAK/STAT pathway in K562 leukemic cells. 2014 Aug 1
13 23279849 Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1. 2013 Apr 1 1
14 19608275 Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition. 2010 Jan 1
15 20663948 Constitutive and B-cell receptor-induced activation of STAT3 are important signaling pathways targeted by bortezomib in leukemic mantle cell lymphoma. 2010 Nov 4
16 19331127 Bortezomib therapeutic effect is associated with expression of FGFR3 in multiple myeloma cells. 2009 Jan 2
17 19638453 Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death. 2009 Aug 13
18 18690088 Blockage of interleukin-6 signaling with 6-amino-4-quinazoline synergistically induces the inhibitory effect of bortezomib in human U266 cells. 2008 Sep 1
19 19383353 Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells. 2008 Dec 1
20 14627979 Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma. 2003 Nov 20 2