Bortezomib

ATP binding cassette subfamily B member 1 ; Homo sapiens







23 Article(s)
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Pub. Year
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1 34915026 Dependence of ABCB1 transporter expression and function on distinct sphingolipids generated by ceramide synthases-2 and -6 in chemoresistant renal cancer. 2022 Feb 1
2 33668794 The Prognostic Value of Whole-Blood PSMB5, CXCR4, POMP, and RPL5 mRNA Expression in Patients with Multiple Myeloma Treated with Bortezomib. 2021 Feb 25 1
3 33860196 Inhibition of P-Glycoprotein Does Not Increase the Efficacy of Proteasome Inhibitors in Multiple Myeloma Cells. 2021 Apr 9 1
4 30365089 Mechanisms underlying the increased chemosensitivity of bortezomib-resistant multiple myeloma by silencing nuclear transcription factor Snail1. 2019 Jan 1
5 29766327 Characterization of carfilzomib-resistant non-small cell lung cancer cell lines. 2018 Jul 1
6 30441975 Selected Genetic Polymorphisms Associated with Hypoxia and Multidrug Resistance in Monoclonal Gammopathies Patients. Spring 2018 1
7 27813130 P-Glycoprotein Inhibition Sensitizes Human Breast Cancer Cells to Proteasome Inhibitors. 2017 May 1
8 28000886 hsa-miR-631 resensitizes bortezomib-resistant multiple myeloma cell lines by inhibiting UbcH10. 2017 Feb 2
9 28509582 Tariquidar sensitizes multiple myeloma cells to proteasome inhibitors via reduction of hypoxia-induced P-gp-mediated drug resistance. 2017 Dec 2
10 25477008 Cellular uptake kinetics of bortezomib in relation to efficacy in myeloma cells and the influence of drug transporters. 2015 Feb 1
11 25576094 Preferential cytotoxicity of bortezomib toward highly malignant human liposarcoma cells via suppression of MDR1 expression and function. 2015 Feb 15 4
12 25590413 Wnt pathway activation and ABCB1 expression account for attenuation of proteasome inhibitor-mediated apoptosis in multidrug-resistant cancer cells. 2015 1
13 24899604 Molecular mechanisms of converting K562/DNR cellular drug-resistance by bortezomib. 2014 4
14 25216523 Proteasome inhibition reverses hedgehog inhibitor and taxane resistance in ovarian cancer. 2014 Aug 30 2
15 23589314 The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias. 2013 May 10
16 22145750 Proteasome inhibitor bortezomib overcomes P-gp-mediated multidrug resistance in resistant leukemic cell lines. 2012 Jun 3
17 22235146 Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with rheumatoid arthritis. 2012 Apr 1
18 22512091 The proteasome inhibitor bortezomib reverses P-glycoprotein-mediated leukemia multi-drug resistance through the NF-kappaB pathway. 2012 Feb 5
19 22082269 Influence of proteasome inhibitor bortezomib on the expression of multidrug resistance genes and Akt kinase activity. 2011 Sep 3
20 19254348 The effects of proteasome inhibitor bortezomib on a P-gp positive leukemia cell line K562/A02. 2010 Feb 3
21 20532504 Polymorphisms in the multiple drug resistance protein 1 and in P-glycoprotein 1 are associated with time to event outcomes in patients with advanced multiple myeloma treated with bortezomib and pegylated liposomal doxorubicin. 2010 Nov 5
22 17096161 Bortezomib activity and in vitro interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are independent of multidrug resistance mechanisms and p53 status. 2007 Jul 2
23 17662692 Knockdown of PgP resensitizes leukemic cells to proteasome inhibitors. 2007 Sep 21 5