Bortezomib

H3 histone pseudogene 16 ; Homo sapiens







35 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32551032 BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis. 2020 1
2 28055975 Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells. 2017 Feb 21 3
3 28161489 Antiproliferative effects of Bortezomib in endothelial cells transformed by viral G protein-coupled receptor associated to Kaposi's sarcoma. 2017 Apr 2
4 26025442 Identification of markers that functionally define a quiescent multiple myeloma cell sub-population surviving bortezomib treatment. 2015 May 30 2
5 26378933 Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma. 2015 5
6 24380881 HO-1 up-regulation: a key point in high-risk neuroblastoma resistance to bortezomib. 2014 Apr 2
7 24485799 Romidepsin induces cell cycle arrest, apoptosis, histone hyperacetylation and reduces matrix metalloproteinases 2 and 9 expression in bortezomib sensitized non-small cell lung cancer cells. 2014 Apr 2
8 23064281 Sequential effects of the proteasome inhibitor bortezomib and chemotherapeutic agents in uterine cervical cancer cell lines. 2013 Jan 1
9 23449448 Phosphorylation of signal transducer and activator of transcription 1 reduces bortezomib-mediated apoptosis in cancer cells. 2013 Feb 28 1
10 23716467 Bortezomib induces apoptosis of endometrial cancer cells through microRNA-17-5p by targeting p21. 2013 Oct 5
11 23903894 Vorinostat in combination with bortezomib in patients with advanced malignancies directly alters transcription of target genes. 2013 Sep 1
12 24263099 Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation. 2013 Nov 21 1
13 22231280 The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma. 2012 Jun 1
14 22324515 Bortezomib reverses the proliferative and antiapoptotic effect of neuropeptides on prostate cancer cells. 2012 Jun 1
15 22559167 Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model. 2012 May 4 1
16 21429402 [In vitro synergistic effect of bortezomib and pirarubicin on proliferation and apoptosis of T cell lymphoma cell line Hut-78 cells]. 2011 Jan 1
17 22087283 The proteasome inhibitor bortezomib enhances ATRA-induced differentiation of neuroblastoma cells via the JNK mitogen-activated protein kinase pathway. 2011 1
18 22169296 [Mechanism associated to enhancing the sensitivity of myeloma cells U266 to bortezomib by 2-methoxyestradiol]. 2011 Dec 1
19 19608275 Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition. 2010 Jan 1
20 20383943 Bortezomib induces apoptosis in human neuroblastoma CHP126 cells. 2010 Mar 1
21 20397022 Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. 2010 Jul 1
22 19661301 Inhibition of proteasome activity by bortezomib in renal cancer cells is p53 dependent and VHL independent. 2009 Aug 1
23 18223318 Proteasome inhibitor Bortezomib induces cell cycle arrest and apoptosis in cell lines derived from Ewing's sarcoma family of tumors and synergizes with TRAIL. 2008 Apr 1
24 18445700 Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. 2008 Jun 1
25 17762396 Antitumor effects and drug interactions of the proteasome inhibitor bortezomib (PS341) in gastric cancer cells. 2007 Jul 1
26 16849420 Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro. 2006 Oct 1
27 15662128 The proteasome inhibitor bortezomib (PS-341) inhibits growth and induces apoptosis in primary effusion lymphoma cells. 2005 Jan 1
28 16178003 Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies. 2005 Nov 1 1
29 15052205 Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer. 2004 Apr 1
30 15131062 Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. 2004 May 1 1
31 15464472 Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis. 2004 Oct 1
32 12738242 Clinical update: proteasome inhibitors in solid tumors. 2003 May 1
33 14688479 Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells. 2003 Nov-Dec 2
34 11306489 The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. 2001 Apr 1 1
35 11740818 Novel therapies targeting the myeloma cell and its bone marrow microenvironment. 2001 Dec 1