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3457 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 171
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 137
3 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 130
4 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 126
5 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 99
6 X-linked Kx blood group XK_HUMAN XK Homo sapiens 7504 753 98
7 synuclein alpha SYUA_HUMAN SNCA Homo sapiens 6622 1780 97
8 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 96
9 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 83
10 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 73
11 NLR family, pyrin domain containing 3 NLRP3_MOUSE Nlrp3 Mus musculus 216799 1325 73
12 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 73
13 NADPH oxidase 4 NOX4_HUMAN NOX4 Homo sapiens 50507 477 69
14 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 67
15 NLR family pyrin domain containing 3 NLRP3_HUMAN NLRP3 Homo sapiens 114548 1179 65
16 parathyroid hormone PTHY_RAT Pth Rattus norvegicus 24694 652 65
17 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 60
18 catalase CATA_HUMAN CAT Homo sapiens 847 2305 59
19 cytochrome b-245 beta chain CY24B_HUMAN CYBB Homo sapiens 1536 409 57
20 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 50
21 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 48
22 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 46
23 bone gamma-carboxyglutamate protein OSTCN_RAT Bglap Rattus norvegicus 25295 408 46
24 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 46
25 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 44
26 cytochrome b-245, beta polypeptide CY24B_MOUSE Cybb Mus musculus 13058 407 43
27 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 41
28 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 36
29 angiotensinogen ANGT_HUMAN AGT Homo sapiens 183 2109 36
30 insulin INS_HUMAN INS Homo sapiens 3630 7950 35
31 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 35
32 superoxide dismutase 1 SODC_HUMAN SOD1 Homo sapiens 6647 2118 33
33 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 33
34 NFE2 like bZIP transcription factor 2 NF2L2_RAT Nfe2l2 Rattus norvegicus 83619 1416 33
35 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 32
36 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 32
37 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 32
38 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 31
39 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 31
40 NADPH oxidase 4 NOX4_MOUSE Nox4 Mus musculus 50490 285 30
41 superoxide dismutase 2 SODM_HUMAN SOD2 Homo sapiens 6648 841 30
42 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 29
43 NLR family, pyrin domain containing 1A NLR1A_MOUSE Nlrp1a Mus musculus 195046 192 29
44 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 29
45 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 29
46 sirtuin 3 SIR3_HUMAN SIRT3 Homo sapiens 23410 319 28
47 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 28
48 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 28
49 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 28
50 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 27