| Protein Name | transforming growth factor, beta 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 59086 |
| Gene Symbol | Tgfb1 |
| UniProt | P17246 (TGFB1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
1730
Total Number of Articles : 3699 |
Description |
transforming growth factor, beta 1 |
| Gene Summary |
Enables identical protein binding activity and protein N-terminus binding activity. Involved in several processes, including animal organ development; cellular response to hormone stimulus; and regulation of epithelial cell proliferation. Acts upstream of or within positive regulation of smooth muscle cell differentiation. Located in several cellular components, including cell surface; neuronal cell body; and secretory granule. Used to study chronic obstructive pulmonary disease; familial hyperlipidemia; hypertension; proteinuria; and pulmonary fibrosis. Biomarker of several diseases, including allergic rhinitis; artery disease (multiple); cerebrovascular disease (multiple); gastrointestinal system cancer (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; Camurati-Engelmann disease; aphthous stomatitis; artery disease (multiple); and lung disease (multiple). Orthologous to human TGFB1 (transforming growth factor beta 1). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |