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caspase 3 ; Homo sapiens







60 Article(s)
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1 34060394 Britannin a Sesquiterpene Lactone from Inula aucheriana Exerted an Anti-leukemic Effect in Acute Lymphoblastic Leukemia (ALL) Cells and Enhanced the Sensitivity of the Cells to Vincristine. 2022 1
2 33527955 The main anthocyanin monomer of Lycium ruthenicum Murray induces apoptosis through the ROS/PTEN/PI3K/Akt/caspase 3 signaling pathway in prostate cancer DU-145 cells. 2021 Feb 21 1
3 33785100 A Highly Cellular Uptake Ternary Nanocomposite Titanate Nano-Tubes/CuFe₂O₄/Zn-Fe Could Induce Intrinsic Apoptosis of Prostate Cancer Cells: An Extended Study. 2021 Feb 28 1
4 34137412 Near infrared II laser controlled free radical releasing nanogenerator for synergistic nitric oxide and alkyl radical therapy of breast cancer. 2021 Jul 7 1
5 34208283 The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS. 2021 Jun 11 1
6 34369076 Caspase-3-mediated GSDME induced Pyroptosis in breast cancer cells through the ROS/JNK signalling pathway. 2021 Sep 3
7 34510030 Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells. 2021 Sep 12 1
8 34571081 STAT3β disrupted mitochondrial electron transport chain enhances chemosensitivity by inducing pyroptosis in esophageal squamous cell carcinoma. 2021 Dec 1 1
9 34681952 Light Tailoring: Impact of UV-C Irradiation on Biosynthesis, Physiognomies, and Clinical Activities of Morus macroura-Mediated Monometallic (Ag and ZnO) and Bimetallic (Ag-ZnO) Nanoparticles. 2021 Oct 19 1
10 34834392 Effect of UV Irradiation (A and C) on Casuarina equisetifolia-Mediated Biosynthesis and Characterization of Antimicrobial and Anticancer Activity of Biocompatible Zinc Oxide Nanoparticles. 2021 Nov 22 2
11 31030314 Anticancer activity, apoptosis and a structure-activity analysis of a series of 1,4-naphthoquinone-2,3-bis-sulfides. 2020 Apr 1
12 31250150 A genetic origin for acid-base imbalance triggers the mitochondrial damage that explains the autoimmune response and drives to gastric neuroendocrine tumours. 2020 Jan 1
13 32107506 In situ one-step synthesis of polymer-functionalized palladium nanoparticles: an efficient anticancer agent against breast cancer. 2020 Mar 21 1
14 32146648 Inhibition of JNJ-26481585-mediated autophagy induces apoptosis via ROS activation and mitochondrial membrane potential disruption in neuroblastoma cells. 2020 May 1
15 32948186 Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2. 2020 Sep 18 2
16 33022360 Imatinib exhibit synergistic pleiotropy in the prevention of colorectal cancer by suppressing proinflammatory, cell survival and angiogenic signaling. 2020 Dec 1
17 30777466 Bufalin induces apoptosis via mitochondrial ROS-mediated caspase-3 activation in HCT-116 and SW620 human colon cancer cells. 2019 Jul 2
18 31004300 Blocking P2X7 receptor ameliorates oxidized LDL-mediated podocyte apoptosis. 2019 Aug 1
19 31277696 Hedgehog pathway inhibition causes primary follicle atresia and decreases female germline stem cell proliferation capacity or stemness. 2019 Jul 5 1
20 29416349 ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells. 2018 1
21 29940354 C60 fullerene accumulation in human leukemic cells and perspectives of LED-mediated photodynamic therapy. 2018 Aug 20 1
22 30111296 Targeting colorectal cancer cell metabolism through development of cisplatin and metformin nano-cubosomes. 2018 Aug 15 1
23 30125721 Mitochondria-targeting BODIPY-loaded micelles as novel class of photosensitizer for photodynamic therapy. 2018 Sep 5 1
24 30196062 Design, synthesis, and evaluation of chalcone analogues incorporate α,β-Unsaturated ketone functionality as anti-lung cancer agents via evoking ROS to induce pyroptosis. 2018 Sep 5 1
25 27888812 A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice. 2017 Jan 3 1
26 28138562 Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension. 2017 Jan 26 1
27 28417940 Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity. 2017 Apr 12 1
28 28591670 Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells. 2017 Aug 1
29 28592114 Oleanolic acid derivative SZC014 inhibit cell proliferation and induce apoptosis of human breast cancer cells in a ROS-dependent way. 2017 1
30 28636040 Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells. 2017 Jul 19 1
31 26152521 Carnosic acid inhibits STAT3 signaling and induces apoptosis through generation of ROS in human colon cancer HCT116 cells. 2016 Jun 1
32 26612416 Co-delivery of Se nanoparticles and pooled SiRNAs for overcoming drug resistance mediated by P-glycoprotein and class III β-tubulin in drug-resistant breast cancers. 2016 Feb 1
33 26861955 An In Vitro Study of the Neurotoxic Effects of N-Benzylpiperazine: A Designer Drug of Abuse. 2016 May 1
34 25776488 Podophyllotoxin acetate enhances γ-ionizing radiation-induced apoptotic cell death by stimulating the ROS/p38/caspase pathway. 2015 Mar 1
35 25890231 Biocompatible ι-carrageenan-γ-maghemite nanocomposite for biomedical applications - synthesis, characterization and in vitro anticancer efficacy. 2015 Mar 3 1
36 26549478 Resveratrol induces cell death and inhibits human herpesvirus 8 replication in primary effusion lymphoma cells. 2015 Dec 5 1
37 24586814 The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death. 2014 1
38 24717093 Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage. 2014 Apr 22 1
39 25064160 Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis. 2014 Oct 1 2
40 25308836 Inhibition of autophagy by chloroquine potentiates synergistically anti-cancer property of artemisinin by promoting ROS dependent apoptosis. 2014 Dec 1
41 23441212 Autophagy inhibition promotes 5-fluorouraci-induced apoptosis by stimulating ROS formation in human non-small cell lung cancer A549 cells. 2013 1
42 23529952 PEG2000-DPSE-coated quercetin nanoparticles remarkably enhanced anticancer effects through induced programed cell death on C6 glioma cells. 2013 Nov 1
43 23688756 [The mechanisms underlying bone marrow damage by iron overload in pancytopenic patients with positive BMMNC-Coombs test]. 2013 May 1
44 23769964 Role of type-II pathway in apoptotic cell death induction by photosensitized CDRI-97/78 under ambient exposure of UV-B. 2013 Oct 24 1
45 23834359 Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis. 2013 Jul 9 2
46 24077485 Chlorobenzenes, lindane and dieldrin induce apoptotic alterations in human peripheral blood lymphocytes (in vitro study). 2013 Nov 1
47 22739161 [Gambogic acid induces apoptosis of Jurkat cell through the MAPK signal pathway]. 2012 Jun 5
48 20940027 Codonopsis lanceolata extract induces G0/G1 arrest and apoptosis in human colon tumor HT-29 cells--involvement of ROS generation and polyamine depletion. 2011 Jan 1
49 21453688 Vitamin K3-2,3-epoxide induction of apoptosis with activation of ROS-dependent ERK and JNK protein phosphorylation in human glioma cells. 2011 Aug 15 1
50 21543583 Interleukin-12 treatment down-regulates STAT4 and induces apoptosis with increasing ROS production in human natural killer cells. 2011 Jul 1