| Protein Name | bone gamma-carboxyglutamate protein |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25295 |
| Gene Symbol | Bglap |
| UniProt | P04640 (OSTCN_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
408
Total Number of Articles : 719 |
Description |
bone gamma-carboxyglutamate protein |
| Gene Summary |
A structural constituent of bone. Involved in several processes, including osteoblast development; response to hydroxyisoflavone; and response to vitamin. Located in several cellular components, including Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Used to study congenital hypothyroidism and osteoporosis. Biomarker of autosomal dominant hypocalcemia; end stage renal disease; and polycystic kidney disease. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein). [provided by Alliance of Genome Resources, Apr 2022] |
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