CPRiL

SIRT3

sirtuin 3

SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]

• NAD-dependent protein deacetylase sirtuin-3, mitochondrial
• NAD-dependent deacetylase sirtuin-3, mitochondrial
• NAD-dependent protein delactylase sirtuin-3
SIR2-like protein 3
mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
regulatory protein SIR2 homolog 3
silent mating type information regulation 2, S.cerevisiae, homolog 3
sir2-like 3
sirtuin type 3
SIR2L3