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BCL2 associated X, apoptosis regulator ; Homo sapiens







31 Article(s)
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1 34060394 Britannin a Sesquiterpene Lactone from Inula aucheriana Exerted an Anti-leukemic Effect in Acute Lymphoblastic Leukemia (ALL) Cells and Enhanced the Sensitivity of the Cells to Vincristine. 2022 1
2 33054537 Estimation of mandarin peel oil-induced cytotoxicity and genotoxicity in human normal fibroblast and cancerous prostate cell lines. 2021 Feb 1
3 33427275 A lysosomal targeted NIR photosensitizer for photodynamic therapy and two-photon fluorescence imaging. 2021 Jan 28 1
4 34403740 Loss of pro-apoptotic Bax and Bak increases resistance to dihydroartemisinin-mediated cytotoxicity in normoxia but not in hypoxia in HCT116 colorectal cancer cells. 2021 Oct 1
5 32948186 Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2. 2020 Sep 18 2
6 31220110 Green synthesis of silver nanoparticles via Cynara scolymus leaf extracts: The characterization, anticancer potential with photodynamic therapy in MCF7 cells. 2019 1
7 29251335 In vitro and in vivo anticancer effects of marmesin in U937 human leukemia cells are mediated via mitochondrial-mediated apoptosis, cell cycle arrest, and inhibition of cancer cell migration. 2018 Feb 1
8 29416349 ROS-dependent Bax/Bcl2 and caspase 3 pathway-mediated apoptosis induced by zineb in human keratinocyte cells. 2018 1
9 29729479 Palmitate lipotoxicity in enteric glial cells: Lipid remodeling and mitochondrial ROS are responsible for cyt c release outside mitochondria. 2018 Aug 1
10 29960166 ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine. 2018 Oct 5
11 30048924 Novel ruthenium(II) triazine complex [Ru(bdpta)(tpy)]2+ co-targeting drug resistant GRP78 and subcellular organelles in cancer stem cells. 2018 Aug 5 1
12 30498348 Biophysical, bioinformatical, cellular, and molecular investigations on the effects of graphene oxide nanosheets on the hemoglobin structure and lymphocyte cell cytotoxicity. 2018 1
13 27748761 Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury. 2017 Apr 6 1
14 28591670 Novel synthetic analogs of diallyl disulfide triggers cell cycle arrest and apoptosis via ROS generation in MIA PaCa-2 cells. 2017 Aug 1
15 29088756 trans-4,4'-Dihydroxystilbene (DHS) inhibits human neuroblastoma tumor growth and induces mitochondrial and lysosomal damages in neuroblastoma cell lines. 2017 Sep 26 1
16 29383185 GPER-independent inhibition of adrenocortical cancer growth by G-1 involves ROS/Egr-1/BAX pathway. 2017 Dec 29 2
17 26086416 Selective killing of gastric cancer cells by a small molecule targeting ROS-mediated ER stress activation. 2016 Jun 1
18 26472167 PM2.5 induces embryonic growth retardation: Potential involvement of ROS-MAPKs-apoptosis and G0/G1 arrest pathways. 2016 Dec 1
19 26612416 Co-delivery of Se nanoparticles and pooled SiRNAs for overcoming drug resistance mediated by P-glycoprotein and class III β-tubulin in drug-resistant breast cancers. 2016 Feb 1
20 27378626 Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells. 2016 Aug 25 1
21 27891207 The Antiapoptosis Effect of Glycyrrhizate on HepG2 Cells Induced by Hydrogen Peroxide. 2016 1
22 25547582 [Resveratrol alleviates oxidative injury from high glucose-induced human lens epithelial cells and its possible mechanism]. 2014 Oct 1
23 23732520 A diterpenoid derivate compound targets selenocysteine of thioredoxin reductases and induces Bax/Bak-independent apoptosis. 2013 Oct 1
24 23769964 Role of type-II pathway in apoptotic cell death induction by photosensitized CDRI-97/78 under ambient exposure of UV-B. 2013 Oct 24 1
25 22848731 An NQO1-initiated and p53-independent apoptotic pathway determines the anti-tumor effect of tanshinone IIA against non-small cell lung cancer. 2012 1
26 21549799 Olaquindox induces apoptosis through the mitochondrial pathway in HepG2 cells. 2011 Jul 29 1
27 21998736 β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells. 2011 1
28 19113979 Synthesis, oxidant properties, and antitumoral effects of a heteroleptic palladium(II) complex of curcumin on human prostate cancer cells. 2009 Jan 22 1
29 19439215 Selenite induces redox-dependent Bax activation and apoptosis in colorectal cancer cells. 2009 Apr 15 2
30 18695917 Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation. 2008 Sep 1
31 18771651 Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress. 2008 Nov 2