ros

tumor protein p53 ; Homo sapiens







126 Article(s)
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1 35042627 The involvement of ERK1/2 and p38 MAPK in the premature senescence of melanocytes induced by H2O2 through a p53-independent p21 pathway. 2022 Feb 1
2 35065161 Novel imidazo[1,2-a]pyridine derivatives induce apoptosis and cell cycle arrest in non-small cell lung cancer by activating NADPH oxidase mediated oxidative stress. 2022 Apr 1 1
3 35069864 p-Coumaric acid suppresses reactive oxygen species-induced senescence in nucleus pulposus cells. 2022 Feb 1
4 35074406 HIWI2 induces G2/M cell cycle arrest and apoptosis in human fibrosarcoma via the ROS/DNA damage/p53 axis. 2022 Mar 15 2
5 35087226 p53 in ferroptosis regulation: the new weapon for the old guardian. 2022 May 1
6 35215995 Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation. 2022 Feb 15 2
7 33039867 ROS-mediated genotoxic stress is involved in NaAsO2-induced cell cycle arrest, stemness enhancement and chemoresistance of prostate cancer cells in a p53-independent manner. 2021 Jan 15 2
8 33054537 Estimation of mandarin peel oil-induced cytotoxicity and genotoxicity in human normal fibroblast and cancerous prostate cell lines. 2021 Feb 1
9 33347603 Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis. 2021 Mar 1
10 33377976 Sirt3 is critical for p53-mediated ferroptosis upon ROS-induced stress. 2021 May 7 1
11 33396077 Different mechanisms of arsenic related signaling in cellular proliferation, apoptosis and neo-plastic transformation. 2021 Jan 15 1
12 33676890 Citrus-derived DHCP inhibits mitochondrial complex II to enhance TRAIL sensitivity via ROS-induced DR5 upregulation. 2021 Jan-Jun 1
13 33785447 The complexity of p53-mediated metabolic regulation in tumor suppression. 2021 Mar 27 1
14 34301789 Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy. 2021 Dec 1 1
15 34314818 The anti-melanogenic effects of 3-O-ethyl ascorbic acid via Nrf2-mediated α-MSH inhibition in UVA-irradiated keratinocytes and autophagy induction in melanocytes. 2021 Sep 1
16 34331475 Curcumin induced G2/M cycle arrest in SK-N-SH neuroblastoma cells through the ROS-mediated p53 signaling pathway. 2021 Sep 2
17 34343634 Inhibition of ribosomal RNA processing 15 Homolog (RRP15), which is overexpressed in hepatocellular carcinoma, suppresses tumour growth via induction of senescence and apoptosis. 2021 Oct 28 2
18 34485982 Activation of P53 Via Nutlin-3a Reveals Role for P53 In ROS Signaling During Cardiac Differentiation of hiPSCs. 2021 1
19 34653407 Anticancer effect of AZD2461 PARP inhibitor against colon cancer cells carrying wt or dysfunctional p53. 2021 Nov 15 1
20 34878954 Autophagy inhibition mediated by MCOLN1/TRPML1 suppresses cancer metastasis via regulating a ROS-driven TP53/p53 pathway. 2021 Dec 8 6
21 31464976 Lycorine Induces Apoptosis and G1 Phase Arrest Through ROS/p38 MAPK Signaling Pathway in Human Osteosarcoma Cells In Vitro and In Vivo. 2020 Feb 1 2
22 31648639 Functionalization of Silver Nanoparticles Loaded with Paclitaxel-induced A549 Cells Apoptosis Through ROS-Mediated Signaling Pathways 2020 1
23 32092796 Increased miR-34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS-JNK-p53 pathway in Alzheimer's Disease. 2020 Mar 1
24 32256964 DpdtC-Induced EMT Inhibition in MGC-803 Cells Was Partly through Ferritinophagy-Mediated ROS/p53 Pathway. 2020 3
25 32530119 Quercetin exerts bidirectional regulation effects on the efficacy of tamoxifen in estrogen receptor-positive breast cancer therapy: An in vitro study. 2020 Nov 1
26 32630700 The Phytochemical Indicaxanthin Synergistically Enhances Cisplatin-Induced Apoptosis in HeLa Cells via Oxidative Stress-Dependent p53/p21waf1 Axis. 2020 Jul 2 1
27 32687844 The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway. 2020 Sep 1 3
28 32738659 Effective treatment of drug-resistant lung cancer via a nanogel capable of reactivating cisplatin and enhancing early apoptosis. 2020 Oct 4
29 32792943 Metformin Synergistically Enhanced the Antitumor Activity of Celecoxib in Human Non-Small Cell Lung Cancer Cells. 2020 1
30 33302580 Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells. 2020 Dec 8 1
31 33381272 Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro. 2020 1
32 30400061 Species-specific mechanisms of tumor suppression are fundamental drivers of vertebrate speciation: critical implications for the 'war on cancer'. 2019 Feb 1
33 30723502 Autophagy Regulated by Gain of Function Mutant p53 Enhances Proteasomal Inhibitor-Mediated Cell Death through Induction of ROS and ERK in Lung Cancer Cells. 2019 1
34 30778058 MiR-135 suppresses glycolysis and promotes pancreatic cancer cell adaptation to metabolic stress by targeting phosphofructokinase-1. 2019 Feb 18 1
35 30895171 Targeting Oxidative Stress With Auranofin or Prima-1Met to Circumvent p53 or Bax/Bak Deficiency in Myeloma Cells. 2019 1
36 31283929 ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro. 2019 Sep 15 2
37 31366086 Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation. 2019 Jul 30 1
38 31391058 Jingfukang induces anti-cancer activity through oxidative stress-mediated DNA damage in circulating human lung cancer cells. 2019 Aug 7 1
39 28918503 CoQ0-induced mitochondrial PTP opening triggers apoptosis via ROS-mediated VDAC1 upregulation in HL-60 leukemia cells and suppresses tumor growth in athymic nude mice/xenografted nude mice. 2018 Jan 1
40 29334793 Controlled synthesis and size effects of multifunctional mesoporous silica nanosystem for precise cancer therapy. 2018 Nov 1
41 29346757 p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells. 2018 Jan 16 1
42 29431732 STAT3/p53 pathway activation disrupts IFN-β-induced dormancy in tumor-repopulating cells. 2018 Mar 1 1
43 29565448 Kaempferol inhibits angiogenic ability by targeting VEGF receptor-2 and downregulating the PI3K/AKT, MEK and ERK pathways in VEGF-stimulated human umbilical vein endothelial cells. 2018 May 1
44 29680675 Far-red light-mediated programmable anti-cancer gene delivery in cooperation with photodynamic therapy. 2018 Jul 3
45 29753331 Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer. 2018 May 12 1
46 29898731 Quercetin inhibits prostate cancer by attenuating cell survival and inhibiting anti-apoptotic pathways. 2018 Jun 14 1
47 30029111 Silica - A trace geogenic element with emerging nephrotoxic potential. 2018 Dec 15 1
48 30029680 Regulation of tNOX expression through the ROS-p53-POU3F2 axis contributes to cellular responses against oxaliplatin in human colon cancer cells. 2018 Jul 20 6
49 30196236 The Mutant p53-Targeting Compound APR-246 Induces ROS-Modulating Genes in Breast Cancer Cells. 2018 Dec 1
50 30265530 N-O Reduction and ROS-Mediated AKT/FOXO1 and AKT/P53 Pathways Are Involved in Growth Promotion and Cytotoxicity of Cyadox. 2018 Nov 19 2