| Protein Name | heme oxygenase 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15368 |
| Gene Symbol | Hmox1 |
| UniProt | P14901 (HMOX1_MOUSE), Q3U5U6 (Q3U5U6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
1339
Total Number of Articles : 2257 |
Description |
heme oxygenase 1 |
| Gene Summary |
Predicted to enable several functions, including heme binding activity; heme oxygenase (decyclizing) activity; and protein homodimerization activity. Acts upstream of or within several processes, including cellular response to cisplatin; cellular response to metal ion; and regulation of macroautophagy. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Used to study hemochromatosis and malaria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and sickle cell anemia. Orthologous to human HMOX1 (heme oxygenase 1). [provided by Alliance of Genome Resources, Apr 2022] |
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