| Protein Name | heme oxygenase 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15368 |
| Gene Symbol | Hmox1 |
| UniProt | P14901 (HMOX1_MOUSE), Q3U5U6 (Q3U5U6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
1339
Total Number of Articles : 2257 |
Description |
heme oxygenase 1 |
| Gene Summary |
Enables heme oxygenase (decyclizing) activity. Involved in heme catabolic process and negative regulation of cytokine production involved in inflammatory response. Acts upstream of or within several processes, including cellular response to cadmium ion; cellular response to cisplatin; and regulation of macroautophagy. Located in nucleus. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study hemochromatosis and malaria. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); factor VIII deficiency; lung disease (multiple); and sickle cell anemia. Orthologous to human HMOX1 (heme oxygenase 1). [provided by Alliance of Genome Resources, Jun 2025] |
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