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AKT serine/threonine kinase 1 ; Homo sapiens







137 Article(s)
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1 34708887 NADPH oxidases regulate endothelial inflammatory injury induced by PM2.5 via AKT/eNOS/NO axis. 2022 May 1
2 34843737 The effects of UVB irradiance on aberrant epidermal proliferation: Novel insights on how to improve currently available sunscreens. 2022 Jan 1 1
3 34847624 Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis. 2022 Jan 1
4 34901534 High-performance SOD mimetic enzyme Au@Ce for arresting cell cycle and proliferation of acute myeloid leukemia. 2022 Apr 1
5 34963561 CREB/Sp1-mediated MCL1 expression and NFκB-mediated ABCB1 expression modulate the cytotoxicity of daunorubicin in chronic myeloid leukemia cells. 2022 Jan 15 1
6 35191133 Glucosamine suppresses oxidative stress and induces protective autophagy in osteoblasts by blocking the ROS/Akt/mTOR signaling pathway. 2022 May 1
7 35204104 Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway. 2022 Jan 24 1
8 35278669 ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury. 2022 May 1
9 35402865 Calcineurin/NFATc2 and PI3K/AKT signaling maintains β-cell identity and function during metabolic and inflammatory stress. 2022 Apr 15 1
10 35450413 Kindlin-2 Promotes Chondrogenesis and Ameliorates IL-1beta-Induced Inflammation in Chondrocytes Cocultured with BMSCs in the Direct Contact Coculture System. 2022 1
11 35500642 Astaxanthin ameliorates hyperglycemia induced inflammation via PI3K/Akt-NF-κB signaling in ARPE-19 cells and diabetic rat retina. 2022 Jul 5 1
12 35525345 Arsenic exposure elevated ROS promotes energy metabolic reprogramming with enhanced AKT-dependent HK2 expression. 2022 Aug 25 3
13 35573641 Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways. 2022 Apr 1
14 35617999 CORM-2 prevents human gingival fibroblasts from lipoteichoic acid-induced VCAM-1 and ICAM-1 expression by inhibiting TLR2/MyD88/TRAF6/PI3K/Akt/ROS/NF-κB signaling pathway. 2022 Jul 1
15 33217539 Eldecalcitol induces apoptosis and autophagy in human osteosarcoma MG-63 cells by accumulating ROS to suppress the PI3K/Akt/mTOR signaling pathway. 2021 Feb 2
16 33397994 Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages. 2021 Jan 4 1
17 33486268 Daphnetin triggers ROS-induced cell death and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway in ovarian cancer. 2021 Feb 1
18 33503015 Correction for: Taurine suppresses ROS-dependent autophagy via activating Akt/mTOR signaling pathway in calcium oxalate crystals-induced renal tubular epithelial cell injury. 2021 Jan 27 1
19 33527955 The main anthocyanin monomer of Lycium ruthenicum Murray induces apoptosis through the ROS/PTEN/PI3K/Akt/caspase 3 signaling pathway in prostate cancer DU-145 cells. 2021 Feb 21 1
20 33577944 Cigarette smoke extract amplifies NADPH oxidase-dependent ROS production to inactivate PTEN by oxidation in BEAS-2B cells. 2021 Apr 2
21 33780455 CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression. 2021 1
22 33791071 Pegylated Recombinant Human Arginase 1 Induces Autophagy and Apoptosis via the ROS-Activated AKT/mTOR Pathway in Bladder Cancer Cells. 2021 2
23 33799790 Tioconazole and Chloroquine Act Synergistically to Combat Doxorubicin-Induced Toxicity via Inactivation of PI3K/AKT/mTOR Signaling Mediated ROS-Dependent Apoptosis and Autophagic Flux Inhibition in MCF-7 Breast Cancer Cells. 2021 Mar 11 1
24 33859780 Zoledronic Acid Enhanced the Antitumor Effect of Cisplatin on Orthotopic Osteosarcoma by ROS-PI3K/AKT Signaling and Attenuated Osteolysis. 2021 1
25 33877317 Purpurin, a anthraquinone induces ROS-mediated A549 lung cancer cell apoptosis via inhibition of PI3K/AKT and proliferation. 2021 Jul 7 1
26 33964994 CN-3 induces mitochondrial apoptosis in glioma via Ros-mediated PI3K/AKT pathway. 2021 May 1 1
27 33977107 Cannabinoid WIN 55,212-2 Inhibits Human Glioma Cell Growth by Triggering ROS-Mediated Signal Pathways. 2021 1
28 34311033 TRPC3 promotes tumorigenesis of gastric cancer via the CNB2/GSK3β/NFATc2 signaling pathway. 2021 Oct 28 1
29 34337709 MiR-124 affects the apoptosis of brain vascular endothelial cells and ROS production through regulating PI3K/AKT signaling pathway. 2021 Jul 1
30 34387860 AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation. 2021 Oct 1
31 34468815 Cobalt-induced oxidative stress contributes to alveolar/bronchiolar carcinogenesis in B6C3F1/N mice. 2021 Oct 1
32 34951363 Free radicals and oxidative stress: signaling mechanisms, redox basis for human diseases, and cell cycle regulation. 2021 Dec 22 1
33 31648639 Functionalization of Silver Nanoparticles Loaded with Paclitaxel-induced A549 Cells Apoptosis Through ROS-Mediated Signaling Pathways 2020 1
34 31987842 Piperlongumine induces apoptosis and G2/M phase arrest in human osteosarcoma cells by regulating ROS/PI3K/Akt pathway. 2020 Jun 3
35 32121588 Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-α. 2020 Mar 1 1
36 32289613 PDGFRα/β-PI3K-Akt pathway response to the interplay of mitochondrial dysfunction and DNA damage in Aroclor 1254-exposed porcine granulosa cells. 2020 Aug 1
37 32467587 Molecular mechanisms of methylglyoxal-induced aortic endothelial dysfunction in human vascular endothelial cells. 2020 May 28 2
38 32687844 The vicious cycle between ferritinophagy and ROS production triggered EMT inhibition of gastric cancer cells was through p53/AKT/mTor pathway. 2020 Sep 1 1
39 32687961 Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells. 2020 Oct 15 1
40 32738660 Hierarchically constructed selenium-doped bone-mimetic nanoparticles promote ROS-mediated autophagy and apoptosis for bone tumor inhibition. 2020 Oct 1
41 32768820 Chlorpyrifos induces the apoptosis and necroptosis of L8824 cells through the ROS/PTEN/PI3K/AKT axis. 2020 Nov 5 1
42 32786113 FOXO3a accumulation and activation accelerate oxidative stress-induced podocyte injury. 2020 Oct 1
43 32931452 Taurine suppresses ROS-dependent autophagy via activating Akt/mTOR signaling pathway in calcium oxalate crystals-induced renal tubular epithelial cell injury. 2020 Sep 15 2
44 33035517 Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells. 2020 Nov 1 1
45 33059314 Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner. 2020 Oct 1
46 33097188 Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells. 2020 Dec 17 1
47 33105741 The Budesonide-Hydroxypropyl-β-Cyclodextrin Complex Attenuates ROS Generation, IL-8 Release and Cell Death Induced by Oxidant and Inflammatory Stress. Study on A549 and A-THP-1 Cells. 2020 Oct 22 1
48 33376580 The Degree of Helicobacter pylori Infection Affects the State of Macrophage Polarization through Crosstalk between ROS and HIF-1α. 2020 2
49 30342220 Effects of 2-aryl-1-cyano-1,2,3,4-tetrohydroisoquinolines on apoptosis induction mechanism in NB4 and MKN-45 cells. 2019 Feb 1
50 30629695 Retraction: Human Phosphatidylethanolamine-Binding Protein 4 Promoted the Radioresistance of Human Rectal Cancer by Activating Akt in an ROS-Dependent Way. 2019 1