Cisplatin


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5829 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 886
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 518
3 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 433
4 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 367
5 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 287
6 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 235
7 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 232
8 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 176
9 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 171
10 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 163
11 translocase of inner mitochondrial membrane 8A TIM8A_HUMAN TIMM8A Homo sapiens 1678 214 161
12 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 160
13 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 160
14 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 157
15 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 149
16 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 140
17 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 135
18 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 121
19 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 118
20 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 111
21 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 109
22 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 105
23 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 103
24 solute carrier family 31 member 1 COPT1_HUMAN SLC31A1 Homo sapiens 1317 119 97
25 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 94
26 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 91
27 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 91
28 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 88
29 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 87
30 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 85
31 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 82
32 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 82
33 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 81
34 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 80
35 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 75
36 X-linked inhibitor of apoptosis XIAP_HUMAN XIAP Homo sapiens 331 647 75
37 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 72
38 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 72
39 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 71
40 ATP binding cassette subfamily C member 2 MRP2_HUMAN ABCC2 Homo sapiens 1244 684 70
41 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 70
42 erythropoietin EPO_HUMAN EPO Homo sapiens 2056 1312 68
43 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 67
44 CD44 molecule (Indian blood group) CD44_HUMAN CD44 Homo sapiens 960 1234 66
45 tumor protein p73 P73_HUMAN TP73 Homo sapiens 7161 217 66
46 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 66
47 colony stimulating factor 3 CSF3_HUMAN CSF3 Homo sapiens 1440 955 65
48 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 65
49 ATP binding cassette subfamily C member 1 MRP1_HUMAN ABCC1 Homo sapiens 4363 1125 64
50 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 63