| 1 |
35505963 | miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways. | 2022 Jun 14 |
3 |
| 2 |
33272936 | Differential Effects of Clinically Relevant N- versus C-Terminal Truncating CDKN1A Mutations on Cisplatin Sensitivity in Bladder Cancer. | 2021 Mar |
7 |
| 3 |
33906321 | Epigallocatechin Gallate Enhances Inhibition Effect of DDP on the Proliferation of Gastric Cancer BGC-823 Cells by Regulating p19Arf-p53-p21Cip1 Signaling Pathway. | 2021 Apr 1 |
1 |
| 4 |
33994369 | Cisplatin Activates the Growth Inhibitory Signaling Pathways by Enhancing the Production of Reactive Oxygen Species in Non-small Cell Lung Cancer Carrying an EGFR Exon 19 Deletion. | 2021 May-Jun |
1 |
| 5 |
34261004 | Cisplatin's potential for type 2 diabetes repositioning by inhibiting CDKN1A, FAS, and SESN1. | 2021 Aug |
4 |
| 6 |
34445588 | Molecular Mechanisms of Chemoresistance Induced by Cisplatin in NSCLC Cancer Therapy. | 2021 Aug 18 |
2 |
| 7 |
34789301 | Ghrelin enhances cisplatin sensitivity in HO-8910 PM human ovarian cancer cells. | 2021 Nov 17 |
1 |
| 8 |
34798882 | MiR-149-3p promotes the cisplatin resistance and EMT in ovarian cancer through downregulating TIMP2 and CDKN1A. | 2021 Nov 19 |
2 |
| 9 |
34873472 | CDKN1A/p21WAF1, RB1, ARID1A, FLG, and HRNR mutation patterns provide insights into urinary tract environmental exposure carcinogenesis and potential treatment strategies. | 2021 |
1 |
| 10 |
32236605 | CDKN1A upregulation and cisplatin‑pemetrexed resistance in non‑small cell lung cancer cells. | 2020 Jun |
1 |
| 11 |
33174043 | Identifying the mechanisms underlying the protective effect of tetramethylpyrazine against cisplatin‑induced in vitro ototoxicity in HEI‑OC1 auditory cells using gene expression profiling. | 2020 Dec |
2 |
| 12 |
33277461 | Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer. | 2020 Dec 4 |
1 |
| 13 |
31127646 | Identification of reciprocal microRNA-mRNA pairs associated with metastatic potential disparities in human prostate cancer cells and signaling pathway analysis. | 2019 Oct |
1 |
| 14 |
31285951 | Genome-scale CRISPR activation screening identifies a role of ELAVL2-CDKN1A axis in paclitaxel resistance in esophageal squamous cell carcinoma. | 2019 |
1 |
| 15 |
31380278 | European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects. | 2019 |
2 |
| 16 |
28081228 | Resistance for Genotoxic Damage in Mesenchymal Stromal Cells Is Increased by Hypoxia but Not Generally Dependent on p53-Regulated Cell Cycle Arrest. | 2017 |
1 |
| 17 |
28842166 | The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer. | 2017 Oct 15 |
1 |
| 18 |
29871302 | [Metformin's effect on 5-fluorouracil,cisplatin,paclitaxel in laryngocarcinoma Hep-2 cells]. | 2017 Apr 5 |
1 |
| 19 |
26392091 | Influence of selected anti-cancer drugs on the induction of DNA double-strand breaks and changes in gene expression in human hepatoma HepG2 cells. | 2016 Aug |
1 |
| 20 |
26984736 | Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation. | 2016 Jun 1 |
10 |
| 21 |
27559850 | DNA damage responsive miR-33b-3p promoted lung cancer cells survival and cisplatin resistance by targeting p21WAF1/CIP1. | 2016 Nov |
3 |
| 22 |
26482648 | The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer. | 2015 Oct 19 |
2 |
| 23 |
24921914 | MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G₁/S transition and apoptosis by targeting p21(WAF1/CIP1). | 2014 Jul 15 |
1 |
| 24 |
23397083 | Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogs. | 2013 Mar |
3 |
| 25 |
23560058 | Two 4N cell-cycle arrests contribute to cisplatin-resistance. | 2013 |
1 |
| 26 |
24155936 | The long noncoding RNA HOTAIR contributes to cisplatin resistance of human lung adenocarcinoma cells via downregualtion of p21(WAF1/CIP1) expression. | 2013 |
8 |
| 27 |
22673193 | Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition. | 2012 Jun 7 |
3 |
| 28 |
23165211 | Pro- and anti-apoptotic effects of p53 in cisplatin-treated human testicular cancer are cell context-dependent. | 2012 Dec 15 |
2 |
| 29 |
21325496 | Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicity. | 2011 May |
10 |
| 30 |
21592546 | The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog. | 2011 Aug |
4 |
| 31 |
21843532 | Genistein, isoflavonoids in soybeans, prevents the formation of excess radiation-induced centrosomes via p21 up-regulation. | 2011 Nov 1 |
1 |
| 32 |
20459793 | Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc. | 2010 May 11 |
1 |
| 33 |
20811155 | Cytoplasmic p21 expression levels determine cisplatin resistance in human testicular cancer. | 2010 Oct |
6 |
| 34 |
21087528 | p21WAF1/CIP1 gene transcriptional activation exerts cell growth inhibition and enhances chemosensitivity to cisplatin in lung carcinoma cell. | 2010 Nov 19 |
2 |
| 35 |
19177004 | Long-term downregulation of Polo-like kinase 1 increases the cyclin-dependent kinase inhibitor p21(WAF1/CIP1). | 2009 Feb 1 |
1 |
| 36 |
18458079 | Cdc6 determines utilization of p21(WAF1/CIP1)-dependent damage checkpoint in S phase cells. | 2008 Jun 27 |
1 |
| 37 |
18483502 | A dual role of p21waf1/cip1 gene in apoptosis of HEp-2 treated with cisplatin or methotrexate. | 2008 Sep |
2 |
| 38 |
18499163 | Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53. | 2008 Jul |
2 |
| 39 |
17582213 | The radiation-induced cell-death signaling pathway is activated by concurrent use of cisplatin in sequential biopsy specimens from patients with cervical cancer. | 2007 Jun |
1 |
| 40 |
16914540 | Dependence of cisplatin-induced cell death in vitro and in vivo on cyclin-dependent kinase 2. | 2006 Sep |
4 |
| 41 |
15840769 | Identification of the functional domain of p21(WAF1/CIP1) that protects cells from cisplatin cytotoxicity. | 2005 Sep |
7 |
| 42 |
15886465 | Effects of cisplatin, 5-fluorouracil, and radiation on cell cycle regulation and apoptosis in the hypopharyngeal carcinoma cell line. | 2005 May |
4 |
| 43 |
15920103 | Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei. | 2005 May 26 |
3 |
| 44 |
14576150 | Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines. | 2004 Jan 2 |
13 |
| 45 |
12594211 | Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response. | 2003 Apr 25 |
1 |
| 46 |
12740909 | Development of resistance to a trinuclear platinum complex in ovarian carcinoma cells. | 2003 Jul 10 |
4 |
| 47 |
12824923 | Enhanced sensitivity to cis-diamminedichloroplatinum(II) of a human carcinoma cell line with mutated p53 gene by cyclin-dependent kinase inhibitor p21(WAF1) expression. | 2003 Mar |
8 |
| 48 |
14513366 | Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents. | 2003 Dec |
6 |
| 49 |
15314975 | Expression of p21 and bcl-2 proteins in paraffin-embedded preparations of non-small cell lung cancer in stage IIIA after Etoposide and Cisplatin induced chemotherapy. | 2003 |
1 |
| 50 |
11734333 | Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells. | 2002 Jan 10 |
5 |