Cisplatin

BRCA1 DNA repair associated ; Homo sapiens







157 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35425960 Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification. 2022 Apr 15 1
2 35541909 TRIM44 promotes BRCA1 functions in HR repair to induce Cisplatin Chemoresistance in Lung Adenocarcinoma by Deubiquitinating FLNA. 2022 5
3 33397362 O6-methylguanine-DNA methyltransferase modulates cisplatin-induced DNA double-strand breaks by targeting the homologous recombination pathway in nasopharyngeal carcinoma. 2021 Jan 4 3
4 33439503 Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells. 2021 Feb 1
5 33536037 Neoadjuvant therapy of BRCA1-driven ovarian cancer by combination of cisplatin, mitomycin C and doxorubicin. 2021 Feb 3 1
6 33619228 Comprehensive Mutational Analysis of the BRCA1-Associated DNA Helicase and Tumor-Suppressor FANCJ/BACH1/BRIP1. 2021 Jun 1
7 33744950 Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aberrancies. 2021 May 7 1
8 33753748 Cisplatin +/- rucaparib after preoperative chemotherapy in patients with triple-negative or BRCA mutated breast cancer. 2021 Mar 22 1
9 33996534 The Efficacy of Combined Cisplatin and Nanoparticle Albumin-Bound Paclitaxel in a Stage IV Pancreatic Squamous Cell Carcinoma Patient With a Somatic BRCA2 Mutation: A Case Report. 2021 1
10 34123730 Effect of cisplatin on metastatic castration-resistant prostate cancer with BRCA2 mutation: A case report. 2021 Sep 1
11 31639439 RAD6B is a major mediator of triple negative breast cancer cisplatin resistance: Regulation of translesion synthesis/Fanconi anemia crosstalk and BRCA1 independence. 2020 Jan 1 4
12 31962039 Impressive effect of cisplatin monotherapy on a patient with heavily pretreated triple-negative breast cancer with poor performance. 2020 Jul 1
13 32000125 lncRNA CISAL Inhibits BRCA1 Transcription by Forming a Tertiary Structure at Its Promoter. 2020 Feb 21 2
14 32092597 Association of BRCA Mutations and BRCAness Status With Anticancer Drug Sensitivities in Triple-Negative Breast Cancer Cell Lines 2020 Jun 5
15 32097728 Downregulation of METTL14 increases apoptosis and autophagy induced by cisplatin in pancreatic cancer cells. 2020 May 1
16 32166000 Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment. 2020 Feb 25 1
17 32277928 A lncRNA Decoy Predicts Sensitivity to Cisplatin. 2020 Apr 1
18 32405340 Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line. 2020 May 5 1
19 32407212 Cisplatin Plus Gemcitabine as Standard of Care for Germline BRCA/PALB2-Mutated Pancreatic Adenocarcinoma: Are We Moving Too Fast? 2020 Jul 20 1
20 32516091 Neoadjuvant Cisplatin in BRCA Carriers With HER2-Negative Breast Cancer. 2020 Aug 10 1
21 32591974 Mitomycin C plus cisplatin for systemic treatment of recurrent BRCA1-associated ovarian cancer. 2020 Dec 2
22 32816949 A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer. 2020 Oct 15 1
23 33030583 Targeting MALAT1 induces DNA damage and sensitize non-small cell lung cancer cells to cisplatin by repressing BRCA1. 2020 Nov 1
24 33074587 EBV-encoded miRNAs can sensitize nasopharyngeal carcinoma to chemotherapeutic drugs by targeting BRCA1. 2020 Nov 1
25 30538112 Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer. 2019 Apr 15 1
26 30579971 XPC deficiency leads to centrosome amplification by inhibiting BRCA1 expression upon cisplatin-mediated DNA damage in human bladder cancer. 2019 Mar 1 1
27 30636383 BRCA1 affects the resistance and stemness of SKOV3-derived ovarian cancer stem cells by regulating autophagy. 2019 Feb 1
28 30705591 RAP80 expression in breast cancer and its relationship with apoptosis in breast cancer cells. 2019 1
29 30770823 Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer. 2019 Feb 15 1
30 30975989 Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma. 2019 Apr 11 1
31 31273933 Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. 2019 Jul 1
32 31556584 pH-Sensitive Shell-Core Platform Block DNA Repair Pathway To Amplify Irreversible DNA Damage of Triple Negative Breast Cancer. 2019 Oct 23 1
33 31807162 The inhibitory effects of cisplatin-radiation combination treatment on malignant osteosarcoma MG-63 cells and BRCA1-p53 pathways are more efficient than single treatments. 2019 Dec 7
34 29247441 Predictors of survival for breast cancer patients with a BRCA1 mutation. 2018 Apr 1
35 29686231 Tamoxifen-resistant breast cancer cells are resistant to DNA-damaging chemotherapy because of upregulated BARD1 and BRCA1. 2018 Apr 23 2
36 29905759 Biomarker assessment of the CBCSG006 trial: a randomized phase III trial of cisplatin plus gemcitabine compared with paclitaxel plus gemcitabine as first-line therapy for patients with metastatic triple-negative breast cancer. 2018 Aug 1 1
37 30247247 Efficacy of Neoadjuvant Therapy With Cisplatin Plus Mitomycin C in BRCA1-Mutated Ovarian Cancer. 2018 Oct 2
38 27130464 Expression of BRCA1, a factor closely associated with relapse-free survival, in patients who underwent neoadjuvant chemotherapy with docetaxel, cisplatin, and fluorouracil for squamous cell carcinoma of the esophagus. 2017 Jan 1
39 27864890 Anti-EGFR monoclonal antibodies enhance sensitivity to DNA-damaging agents in BRCA1-mutated and PTEN-wild-type triple-negative breast cancer cells. 2017 May 1
40 27980104 The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics. 2017 Mar 2
41 28376831 Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair. 2017 Apr 4 1
42 28398198 Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance. 2017 Apr 11 1
43 28427225 Enhancing synthetic lethality of PARP-inhibitor and cisplatin in BRCA-proficient tumour cells with hyperthermia. 2017 Apr 25 1
44 29113350 BRCA1 and STMN1 as prognostic markers in NSCLCs who received cisplatin-based adjuvant chemotherapy. 2017 Oct 6 2
45 29163710 Combination of histoculture drug response assay and qPCR as an effective method to screen biomarkers for personalized chemotherapy in esophageal cancer. 2017 Dec 2
46 26801247 Phase I Study of Veliparib (ABT-888) Combined with Cisplatin and Vinorelbine in Advanced Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer. 2016 Jun 15 1
47 26870207 Analysis of ERCC1, BRCA1, RRM1 and TUBB3 as predictors of prognosis in patients with non-small cell lung cancer who received cisplatin-based adjuvant chemotherapy: A prospective study. 2016 Jan 3
48 27186285 Effect of the BRCA1-SIRT1-EGFR axis on cisplatin sensitivity in ovarian cancer. 2016 6
49 27197267 The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. 2016 May 1 2
50 27313763 Successful personalized chemotherapy for metastatic gastric cancer based on quantitative BRCA1 mRNA expression level: A case report. 2016 Jun 1