Cisplatin

caspase 8 ; Homo sapiens







91 Article(s)
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1 33985619 lncCRLA Enhanced Chemoresistance in Lung Adenocarcinoma That Underwent EpithelialMesenchymal Transition. 2022 Jan 31 1
2 34994335 Novel coumarin derivatives containing a triazole moiety: A study on synthesis, cytotoxicity, membrane dysfunction, apoptosis, cell cycle, and antiangiogenic studies. 2022 Jan 6 1
3 34299199 Ruthenium(II) and Platinum(II) Complexes with Biologically Active Aminoflavone Ligands Exhibit In Vitro Anticancer Activity. 2021 Jul 15 1
4 35070983 Prediction of the Mechanisms by Which Quercetin Enhances Cisplatin Action in Cervical Cancer: A Network Pharmacology Study and Experimental Validation. 2021 1
5 31838086 Cisplatin unleashes Toll-like receptor 3-mediated apoptosis through the downregulation of c-FLIP in malignant mesothelioma. 2020 Mar 1 1
6 32187278 Apoptosis-related gene expression can predict the response of ovarian cancer cell lines to treatment with recombinant human TRAIL alone or combined with cisplatin. 2020 1
7 33194045 Caspase-8 knockdown suppresses apoptosis, while induces autophagy and chemo-sensitivity in non-small cell lung cancer cells. 2020 1
8 30724400 Inhibition of N-myc expression sensitizes human neuroblastoma IMR-32 cells expressing caspase-8 to TRAIL. 2019 May 2
9 30805008 Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin. 2019 2
10 30867764 Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. 2019 Mar 1
11 30868675 Cancer-associated fibroblasts contribute to cisplatin resistance by modulating ANXA3 in lung cancer cells. 2019 May 1
12 30941888 p62 aggregates mediated Caspase 8 activation is responsible for progression of ovarian cancer. 2019 Jun 1
13 30944654 TNFAIP8 promotes cisplatin resistance in cervical carcinoma cells by inhibiting cellular apoptosis. 2019 May 1
14 31571909 Anti-tumor effect of chitin oligosaccharide plus cisplatin in vitro and in vivo. 2019 2
15 31587185 CASP8 (rs3834129) and CASP3 (rs4647601) polymorphisms in oropharynx cancer risk, tumor cell differentiation, and prognosis in a cohort of the Brazilian population. 2019 Dec 1
16 27871859 Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis. 2017 Jan 22 2
17 27993669 Contrasting effects of glutamine deprivation on apoptosis induced by conventionally used anticancer drugs. 2017 Mar 1
18 28107698 The natural flavonoid apigenin sensitizes human CD44+ prostate cancer stem cells to cisplatin therapy. 2017 Apr 1
19 26796280 Lifeguard inhibition of Fas-mediated apoptosis: A possible mechanism for explaining the cisplatin resistance of triple-negative breast cancer cells. 2016 Feb 2
20 27195913 Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src. 2016 Aug 28 2
21 27473145 Hypoxia-induced resistance to cisplatin-mediated apoptosis in osteosarcoma cells is reversed by gambogic acid independently of HIF-1α. 2016 Sep 1
22 27494891 Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells. 2016 Aug 30 1
23 25682199 Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis. 2015 Jan 30 2
24 25770930 Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53. 2015 May 5 1
25 25894537 Loss of α(E)-catenin promotes Fas mediated apoptosis in tubular epithelial cells. 2015 Jul 1
26 26171069 Synergistic effects of cisplatin and proteasome inhibitor bortezomib on human bladder cancer cells. 2015 Jul 1
27 26273359 Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line. 2015 Mar 2
28 24286513 Protective effect of acetyl-l-carnitine against cisplatin ototoxicity: role of apoptosis-related genes and pro-inflammatory cytokines. 2014 Feb 3
29 24507386 Combination therapy of anti-cancer bioactive peptide with Cisplatin decreases chemotherapy dosing and toxicity to improve the quality of life in xenograft nude mice bearing human gastric cancer. 2014 Feb 10 1
30 24519546 RIPK4 is downregulated in poorly differentiated tongue cancer and is associated with migration/invasion and cisplatin-induced apoptosis. 2014 Jun 25 1
31 24894297 Targeting Notch1 signaling pathway positively affects the sensitivity of osteosarcoma to cisplatin by regulating the expression and/or activity of Caspase family. 2014 Jun 3 3
32 25085582 Combination of bladder cancer-specific oncolytic adenovirus gene therapy with cisplatin on bladder cancer in vitro. 2014 Nov 1
33 25216531 Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. 2014 Aug 30 1
34 23564782 β-Elemene promotes cisplatin-induced cell death in human bladder cancer and other carcinomas. 2013 Apr 1
35 23564786 Salinomycin induces apoptosis via death receptor-5 up-regulation in cisplatin-resistant ovarian cancer cells. 2013 Apr 1
36 23826494 Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells. 2013 May 1
37 23830991 Synergistic apoptotic effect of crocin and cisplatin on osteosarcoma cells via caspase induced apoptosis. 2013 Aug 29 1
38 23912708 Combination of Ad-sTRAIL with the chemotherapeutic drug cisplatin synergistically enhances their pro-apoptotic ability in human breast cancer cells. 2013 Oct 1
39 23926438 Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells. 2013 1
40 24309938 Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer. 2013 Dec 5 1
41 22328720 Human papilloma virus 16 E6 RNA interference enhances cisplatin and death receptor-mediated apoptosis in human cervical carcinoma cells. 2012 May 1
42 22431999 Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury. 2012 1
43 23254292 Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer. 2012 Dec 20 3
44 21037225 Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. 2011 Jan 1
45 21052098 Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells. 2011 Mar 1
46 21128834 Specific blockage of caspase-1 activation by purple bamboo-salt prevents apoptosis of auditory cell line, HEI-OC1. 2011 Jan-Feb 1
47 21157427 Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin. 2011 Feb 2 1
48 21214929 α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73. 2011 Jan 7 1
49 21216935 Anticancer activity of a combination of cisplatin and fisetin in embryonal carcinoma cells and xenograft tumors. 2011 Feb 1
50 21487429 Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis. 2011 Apr 12 5