Cisplatin

mitogen-activated protein kinase 3 ; Homo sapiens







80 Article(s)
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1 34890285 Synergistic inhibitory effects of 5-aza-2'-deoxycytidine and cisplatin on urothelial carcinoma growth via suppression of TGFBI-MAPK signaling pathways. 2022 Apr 1
2 35454385 Eribulin Mesylate Improves Cisplatin-Induced Cytotoxicity of Triple-Negative Breast Cancer by Extracellular Signal-Regulated Kinase 1/2 Activation. 2022 Apr 15 3
3 33469371 LncRNA BANCR Attenuates the Killing Capacity of Cisplatin on Gastric Cancer Cell Through the ERK1/2 Pathway. 2021 2
4 33478150 Impact of Selected Signaling Proteins on SNAIL 1 and SNAIL 2 Expression in Ovarian Cancer Cell Lines in Relation to Cells' Cisplatin Resistance and EMT Markers Level. 2021 Jan 19 1
5 33792844 Trans-ferulic acid ameliorates cisplatin-induced testicular damage via suppression of TLR4, P38-MAPK, and ERK1/2 signaling pathways. 2021 Aug 1
6 33813077 Suppressing CHD1L reduces the proliferation and chemoresistance in osteosarcoma. 2021 May 21 1
7 34068624 Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism. 2021 May 10 1
8 34078815 Protective Effect of Panduratin A on Cisplatin-Induced Apoptosis of Human Renal Proximal Tubular Cells and Acute Kidney Injury in Mice. 2021 2
9 34365218 Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. 2021 Nov 1
10 34458953 RETRACTED ARTICLE: Reduced LINC00467 elevates microRNA-125a-3p to suppress cisplatin resistance in non-small cell lung cancer through inhibiting sirtuin 6 and inactivating the ERK1/2 signaling pathway. 2021 Aug 30 1
11 34571081 STAT3β disrupted mitochondrial electron transport chain enhances chemosensitivity by inducing pyroptosis in esophageal squamous cell carcinoma. 2021 Dec 1 1
12 34789301 Ghrelin enhances cisplatin sensitivity in HO-8910 PM human ovarian cancer cells. 2021 Nov 17 1
13 32102425 Non-Phosphorylatable PEA-15 Sensitises SKOV-3 Ovarian Cancer Cells to Cisplatin. 2020 Feb 24 1
14 32766794 Correction: Cisplatin contributes to programmed death-ligand 1 expression in bladder cancer through ERK1/2-AP-1 signaling pathway. 2020 Aug 28 1
15 31022663 Celastrol, a plant-derived triterpene, induces cisplatin-resistance nasopharyngeal carcinoma cancer cell apoptosis though ERK1/2 and p38 MAPK signaling pathway. 2019 May 2
16 31312250 Overexpression of P16 reversed the MDR1-mediated DDP resistance in the cervical adenocarcinoma by activating the ERK1/2 signaling pathway. 2019 2
17 31341011 Cisplatin contributes to programmed death-ligand 1 expression in bladder cancer through ERK1/2-AP-1 signaling pathway. 2019 Sep 30 2
18 31378887 MiR-129 reduces CDDP resistance in gastric cancer cells by inhibiting MAPK3. 2019 Aug 3
19 31440159 The Role of Prostaglandin-Endoperoxide Synthase-2 in Chemoresistance of Non-Small Cell Lung Cancer. 2019 1
20 31518663 Cisplatin induces chemoresistance through the PTGS2-mediated anti-apoptosis in gastric cancer. 2019 Nov 3
21 31538075 Effects of genistein on anti-tumor activity of cisplatin in human cervical cancer cell lines. 2019 Sep 1
22 31798724 Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases. 2019 Dec 1
23 28287251 Cisplatin induced apoptosis of ovarian cancer A2780s cells by activation of ERK/p53/PUMA signals. 2018 Jan 6
24 29130514 Involvement of Src signaling in the synergistic effect between cisplatin and digoxin on cancer cell viability. 2018 Apr 2
25 29247711 Hexokinase 2 confers resistance to cisplatin in ovarian cancer cells by enhancing cisplatin-induced autophagy. 2018 Feb 2
26 29352505 p53-independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells. 2018 Jun 1
27 29372560 Inhibition of the CSF-1 receptor sensitizes ovarian cancer cells to cisplatin. 2018 Mar 1
28 29373150 Overexpressed SIRT6 attenuates cisplatin-induced acute kidney injury by inhibiting ERK1/2 signaling. 2018 Apr 1
29 29565706 LncRNA NEAT1/let-7a-5p axis regulates the cisplatin resistance in nasopharyngeal carcinoma by targeting Rsf-1 and modulating the Ras-MAPK pathway. 2018 Jun 3 2
30 29724868 Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo. 2018 Aug 1 1
31 29731988 Cisplatin-induced ERK1/2 activity promotes G1 to S phase progression which leads to chemoresistance of ovarian cancer cells. 2018 Apr 13 8
32 30522099 miR-202 Enhances the Anti-Tumor Effect of Cisplatin on Non-Small Cell Lung Cancer by Targeting the Ras/MAPK Pathway. 2018 1
33 27995416 Synergistic action of cisplatin and echistatin in MDA-MB-231 breast cancer cells. 2017 Mar 1
34 28598976 The dynamic role of autophagy and MAPK signaling in determining cell fate under cisplatin stress in osteosarcoma cells. 2017 3
35 28703809 Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity. 2017 Jul 13 1
36 29344202 Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2. 2017 Dec 1
37 26331987 Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment. 2016 Mar 1
38 26794135 Knockdown of MACC1 expression increases cisplatin sensitivity in cisplatin-resistant epithelial ovarian cancer cells. 2016 Apr 1
39 27564099 Curcumin potentiates antitumor activity of cisplatin in bladder cancer cell lines via ROS-mediated activation of ERK1/2. 2016 Sep 27 3
40 27656839 Knockdown of PARP-1 Inhibits Proliferation and ERK Signals, Increasing Drug Sensitivity in Osteosarcoma U2OS Cells. 2016 1
41 25765877 Platinum-induced neurotoxicity and preventive strategies: past, present, and future. 2015 Apr 1
42 25770930 Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53. 2015 May 5 1
43 25879333 The effects of combination of gefitinib and cisplatin on tongue squamous cell carcinoma cell lines. 2015 Jan-Mar 1
44 26249763 Relevance of subcellular localization of extracellular signal-regulated kinase 1/2 (ERK1/2) for cisplatin resistance. 2015 Dec 1
45 26300055 PKC-δ/PKC-α activity balance regulates the lethal effects of cisplatin. 2015 Nov 1 1
46 23904094 Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells. 2014 Feb 1 1
47 24751980 Secreted clusterin gene silencing enhances chemosensitivity of a549 cells to cisplatin through AKT and ERK1/2 pathways in vitro. 2014 1
48 24944268 Magnesium protects against cisplatin-induced acute kidney injury by regulating platinum accumulation. 2014 Aug 15 1
49 25099161 PIM2 kinase is induced by cisplatin in ovarian cancer cells and limits drug efficacy. 2014 Nov 7 1
50 25106434 Secreted clusterin (sCLU) regulates cell proliferation and chemosensitivity to cisplatin by modulating ERK1/2 signals in human osteosarcoma cells. 2014 Aug 9 1