Cisplatin

caspase 9 ; Homo sapiens







111 Article(s)
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1 34826159 Mechanism of sensitivity to cisplatin, docetaxel, and 5-fluorouracil chemoagents and potential erbB2 alternatives in oral cancer with growth differentiation factor 15 overexpression. 2022 Feb 1
2 34994335 Novel coumarin derivatives containing a triazole moiety: A study on synthesis, cytotoxicity, membrane dysfunction, apoptosis, cell cycle, and antiangiogenic studies. 2022 Jan 6 1
3 35522909 Exosome-transmitted miR-769-5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53. 2022 May 2
4 35525317 Cisplatin-induced pyroptosis is mediated via the CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME axis in esophageal cancer. 2022 Jul 1 2
5 35599471 Downregulation of ASF1B inhibits tumor progression and enhances efficacy of cisplatin in pancreatic cancer. 2022 May 13 1
6 33441751 Cytoglobin protects cancer cells from apoptosis by regulation of mitochondrial cardiolipin. 2021 Jan 13 1
7 33569751 MicroRNA-143 Sensitizes Cervical Cancer Cells to Cisplatin: a Promising Anticancer Combination Therapy. 2021 Jul 1
8 34036394 CDK4 overexpression is a predictive biomarker for resistance to conventional chemotherapy in patients with osteosarcoma. 2021 Jul 1
9 34183962 The Synergistic Combination of Cisplatin and Piperine Induces Apoptosis in MCF-7 Cell Line. 2021 May 1
10 34206951 Combined Action of Anti-MUC1 Monoclonal Antibody and Pyrazole-Platinum(II) Complexes Reveals Higher Effectiveness towards Apoptotic Response in Comparison with Monotherapy in AGS Gastric Cancer Cells. 2021 Jun 26 1
11 31270811 Caveolin-1 knockdown increases the therapeutic sensitivity of lung cancer to cisplatin-induced apoptosis by repressing Parkin-related mitophagy and activating the ROCK1 pathway. 2020 Feb 1
12 32374939 Protective effect of ginsenoside Rk1, a major rare saponin from black ginseng, on cisplatin-induced nephrotoxicity in HEK-293 cells. 2020 Sep 2
13 32973533 Hesperetin Promotes Cisplatin-Induced Apoptosis of Gastric Cancer In Vitro and In Vivo by Upregulating PTEN Expression. 2020 2
14 33126443 Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways. 2020 Oct 28 1
15 30794682 Growth arrest and DNA damage 45γ is required for caspase-dependent renal tubular cell apoptosis. 2019 2
16 30867764 Efficacy of celastrol combined with cisplatin in enhancing the apoptosis of U-2OS osteosarcoma cells via the mitochondrial and endoplasmic reticulum pathways of apoptosis. 2019 Mar 1
17 31176111 Peptide-functionalized upconversion nanoparticles-based FRET sensing platform for Caspase-9 activity detection in vitro and in vivo. 2019 Sep 15 3
18 31661694 TRIAP1 Inhibition Activates the Cytochrome c/Apaf-1/Caspase-9 Signaling Pathway to Enhance Human Ovarian Cancer Sensitivity to Cisplatin. 2019 2
19 29434943 Mechanism of anticancer action of novel berenil complex of platinum(II) combined with anti-MUC1 in MCF-7 breast cancer cells. 2018 Feb 1
20 29476302 Apoptotic effects of ε-viniferin in combination with cis-platin in C6 cells. 2018 Jun 1
21 30594176 MLH1 enhances the sensitivity of human endometrial carcinoma cells to cisplatin by activating the MLH1/c-Abl apoptosis signaling pathway. 2018 Dec 29 1
22 31938109 Immediate early response gene 5 promotes irradiation combined with cisplatin-induced apoptosis in HeLa cells. 2018 1
23 28123844 Targeting NF-κB/AP-2β signaling to enhance antitumor activity of cisplatin by melatonin in hepatocellular carcinoma cells. 2017 1
24 28124680 Chemosensitizing Effect of Astragalus Polysaccharides on Nasopharyngeal Carcinoma Cells by Inducing Apoptosis and Modulating Expression of Bax/Bcl-2 Ratio and Caspases. 2017 Jan 26 2
25 28207569 Poly ADP-ribose polymerase inhibition suppresses cisplatin toxicity in chronic myeloid leukemia cells. 2017 Mar 1
26 28214344 Neferine Potentiates the Antitumor Effect of Cisplatin in Human Lung Adenocarcinoma Cells Via a Mitochondria-Mediated Apoptosis Pathway. 2017 Sep 1
27 28454332 Zoledronic acid reverses cisplatin resistance in nasopharyngeal carcinoma cells by activating the mitochondrial apoptotic pathway. 2017 Mar 1
28 28502300 [Down-regulation of sphingosine kinase 1 (SphK1) enhances the chemosensitivity to cisplatin in human colon cancer RKO cells]. 2017 May 1
29 26796280 Lifeguard inhibition of Fas-mediated apoptosis: A possible mechanism for explaining the cisplatin resistance of triple-negative breast cancer cells. 2016 Feb 1
30 26984736 Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation. 2016 Jun 1 4
31 27065754 SOX17 increases the cisplatin sensitivity of an endometrial cancer cell line. 2016 1
32 27177238 Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. 2016 Jul 1
33 27419628 Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells. 2016 Aug 23 1
34 27494891 Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells. 2016 Aug 30 1
35 27514524 Quercetin and Cisplatin combined treatment altered cell cycle and mitogen activated protein kinase expressions in malignant mesotelioma cells. 2016 Aug 11 1
36 27601167 Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis. 2016 Dec 1
37 27751820 Inhibition of JNK and prothymosin-alpha sensitizes hepatocellular carcinoma cells to cisplatin. 2016 Dec 15 1
38 25143433 Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms. 2015 Jan 2
39 25770930 Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53. 2015 May 5 1
40 25796504 Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin. 2015 Apr 3
41 26124336 Sulforaphene Synergistically Sensitizes Cisplatin via Enhanced Mitochondrial Dysfunction and PI3K/PTEN Modulation in Ovarian Cancer Cells. 2015 Jul 1
42 23904094 Downregulation of miR-29 contributes to cisplatin resistance of ovarian cancer cells. 2014 Feb 1 1
43 24894297 Targeting Notch1 signaling pathway positively affects the sensitivity of osteosarcoma to cisplatin by regulating the expression and/or activity of Caspase family. 2014 Jun 3 1
44 25085582 Combination of bladder cancer-specific oncolytic adenovirus gene therapy with cisplatin on bladder cancer in vitro. 2014 Nov 1
45 25216531 Apollon modulates chemosensitivity in human esophageal squamous cell carcinoma. 2014 Aug 30 1
46 25622680 [p14ARF enhances chemosensitivity to cisplatin in human osteosarcoma U2OS cells through p53 apoptotic pathway]. 2014 Nov 25 1
47 23252748 Overexpression of Smac promotes Cisplatin-induced apoptosis by activating caspase-3 and caspase-9 in lung cancer A549 cells. 2013 Mar 3
48 23255126 Wild-type and mutant p53 mediate cisplatin resistance through interaction and inhibition of active caspase-9. 2013 Jan 15 2
49 23399702 RETRACTED: Tea polyphenols enhance cisplatin chemosensitivity in cervical cancer cells via induction of apoptosis. 2013 Jul 19 1
50 23534730 Induction of mitochondrial-mediated apoptosis by Morinda citrifolia (Noni) in human cervical cancer cells. 2013 1